Therapeutic Abs Flashcards
1
Q
Targets CD3?
A
Muromonab-CD3 (OKT3)
2
Q
Targets digoxin?
A
Digoxin immune Fab
3
Q
Targets TNF-a?
A
Infliximab, adalimumab
4
Q
Targets gp-IIb/IIIa?
A
Abciximab
5
Q
Targets HER2?
A
Trastuzumab (Herceptin)
6
Q
Targets CD20?
A
Rituximab
7
Q
Targets IgE?
A
Omalizumab
8
Q
Tx for B-cell non-Hodgkin’s lymphoma?
A
Rituximab
9
Q
Used to prevent acute transplant rejection?
A
Muromonab-CD3
10
Q
Tx for Crohn’s, RA, psoriatic arthritis?
A
Infliximab, adalimumab
11
Q
Tx for ankylosing spondylitis?
A
Infliximab
12
Q
Used to prevent cardiac ischemia in unstable angina and in pts treated with percutaneous coronary intervention?
A
Abciximab
13
Q
Used for HER2-overexpressing breast cancer?
A
Trastuzumab
14
Q
Additional line of tx for severe asthma?
A
Omalizumab