Cytokines Flashcards
1
Q
Secreted by macrophages?
A
IL-1, 6, 8, 12, TNF-a
2
Q
Secreted by all T-cells?
A
IL-2, 3
3
Q
Secreted by Th1 cells?
A
IFN-g
4
Q
Secreted by Th2 cells?
A
IL-4, 5, 10
5
Q
Endogenous pyrogen, acts on anterior hypothalamus to increase set point?
A
IL-1 and IL-6
6
Q
Stimulates growth of helper, cytotoxic, and T-reg cells?
A
IL-2
7
Q
Stimulates bone marrow stem cells?
A
IL-3 (acts like GM-CSF)
8
Q
Activates Th1 and NK cells and it also secreted by B-cells?
A
IL-12
9
Q
Mediates septic shock?
A
TNF-a
10
Q
Activates endothelium to express adhesion molecules?
A
IL-1
11
Q
Major chemotactic factor for neutrophils?
A
IL-8
12
Q
Stimulates production of APPs by liver?
A
IL-6
13
Q
Stimulates macrophages?
A
IFN-g
14
Q
Inhibits Th2 cells?
A
IFN-g
15
Q
Enhances class switching to IgE and IgG?
A
IL-4
