theories Flashcards
As pregnancy nears, oxytocin production by the posterior pituitary gland increases while oxytocinase production by the placenta decreases, making the uterus more sensitive to oxytocin, which stimulates uterine contraction.
Oxytocin Stimulation Theory
Any hollow muscular organ, when stretched to capacity, will contract and empty. As pregnancy advances, the distention of the uterus creates pressure on nerve endings, stimulating uterine contraction.
Uterine Stretch Theory
Progesterone maintains pregnancy by relaxing the smooth muscles of the uterus. As pregnancy nears term, progesterone production decreases, leading to uterine contractions.
Progesterone Deprivation Theory
When pregnancy reaches term, fetal membranes produce large amounts of arachidonic acid, which is converted by maternal deciduas into prostaglandin, initiating uterine contractions during labor.
Prostaglandin Theory
As the placenta ages, it becomes less efficient, producing less progesterone and allowing concentrations of prostaglandin and estrogen to rise, resulting in rhythmic, regular, and strong uterine contractions.
Theory of the Aging Placenta
This theory, proposed by Hippocrates, states that certain hormones produced by the fetal adrenal and pituitary glands initiate labor contractions.
Fetal Adrenal Response Theory