Theophylline Flashcards

1
Q

What is it and mechanism

A

xanthine

phosphoesterase inhibiting drug so less cyclic AMP broken down in smooth muscle cells

leads to bronchodilation

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2
Q

indications

A

reversible airway obstruction

chronic asthma
COPD

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3
Q

contraindications (cautions)

A

arrhythmia

epilepsy
hypertension

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4
Q

interactions

A

Antivirals e.g. Aciclovir, valaciclovir

beta blockers e.g. Amiodorane, bisoprolol, digoxin, atenolol, propanolol

macrolide antibiotics e.g. clarythromycin, erythromycin

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5
Q

side effects

A
nausea
d and v
anxiety
arrythmias
GI discomfort/ GORD
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