Theophylline Flashcards
1
Q
What is it and mechanism
A
xanthine
phosphoesterase inhibiting drug so less cyclic AMP broken down in smooth muscle cells
leads to bronchodilation
2
Q
indications
A
reversible airway obstruction
chronic asthma
COPD
3
Q
contraindications (cautions)
A
arrhythmia
epilepsy
hypertension
4
Q
interactions
A
Antivirals e.g. Aciclovir, valaciclovir
beta blockers e.g. Amiodorane, bisoprolol, digoxin, atenolol, propanolol
macrolide antibiotics e.g. clarythromycin, erythromycin
5
Q
side effects
A
nausea d and v anxiety arrythmias GI discomfort/ GORD