Omeprazole Flashcards

1
Q

what is it and mechanism

A

proton pump inhibitor

prevents proton pump which in turn inhibits the secretion of gastric acid

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2
Q

indications

A

GORD

dyspepsia (indigestion)

severe oesophagitis

h pylori eradication (makes environment not suitable for life)

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3
Q

contraindications (cautions)

A

can increase the risk of fractures

increase chance of GI infections

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4
Q

interactions

A

acyclovir (omeprazole increases its metabolism)

apixaban (omeprazole decreases excretion rate of it)

Methotrexate (decreased clearance)

citalopram (SSRI)

tyrosine kinase inhibitors (cancer treatment)

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5
Q

side effects/ patient info

A
headache 
nausea
d and v
stomach pain
constipation
flatuence

jaundice indicates liver problems
joint pain indicates lupus

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