The Upper Respiratory Tract Flashcards
Why is the upper respiratory tract important
Often get infections here (rhinitis, laryngitis, bronchitis)
Generally less severe than lower resp tract where infections here can kill (pneumonia :( )
Describe the structure of the nasal cavities
What is the function of the nasal cavity and the structures inside
Ant nares => Vestibule with vibrisae => Nasal cavity => Post nares
Warms the air
Keeps it moist, both ensure that the moisture in the lungs is 100% saturated with O2
Vibrisae, filters inspired air
Describe the general structure of the whole pharynx
Muscular tube made up of nasal pharynx, oropharynx and hypopharynx
Where can the nasal pharynx be found
Extends from the base of the skull to the upper surface of the soft palate
Opening of auditory tube found here
Where can the oral pharynx be found
Between the soft a palate and superior border of the epiglottis
Where can the hypopharynx be found
Where the pharynx splits into the larynx and oesophagus
Describe the structure and function of the larynx
Made up of hyaline and elastic cartilage
Predominantly a sphincter for the airway, prevent food and fluids entering the lungs
Voice box also found here but not its main role
What is the function of the oesophagus
Food and fluids enter here => GBS
Describe the structure and function of the trachea
20C shaped cartilage rings, keeps airway open
Leads to carina (bifurcation of trachea => 2 bronchi at T4)
How does the bronchus divide and what changes as a result?
Pulmonary bronchus => Lobar bronchus => Segmentary bronchus => etc
23 divisions in total
As you divide, amount of hyaline cartilage decreases, amount of smooth muscle increases, amount of connective tissue increases
Epithelium transitions from ciliates pseudostratified columnar => simple squamous
Start to lose smooth muscle and connective tissue as you approach alveoli, site of gas exchange
Describe the pulmonary circulation (pulmonary arteries, veins, bronchial arteries and veins)
Pulmonary arteries branch along bronchiole very closely
Forms a plexus around alveoli with pulmonary vein capillaries
O2 in solution diffuses across 2nm
Pulmonary vein normally further away from bronchioles
Alveoli don’t need a blood supply, get their O2 from diffusion
Thoracic aorta => bronchial arteries => veins => pulmonary veins, azygos
What are the protective mechanisms of the upper respiratory tract
Mechanical (mucus and hairs) Goblet cells and serous glands Mucociliary escalator and cilia Macrophages WBCs Mast cells and histamine release
How does mechanical protection (mucus and hairs) protect the URT
Moistens air and traps pathogens
How do the goblet cells and serous glands protect the URT
Watery submucosal antibacteriocidal secretions
How does the mucociliary escalator and cilia protect the URT
On top of pseudocolumnar cells, wafts mucus up to oesophagus => stomach from bronchi
How do macrophages help protect the URT
How do WBCs help protect the URT
How do mast cells help protect the URT
Digests unwanted pathogens, travel up to pharynx to dispose of them
Aids in immune response
Mast cells release histamine, decreases lumen in airway, prevent pathogens from entering the lumen
Describe how airflow is directed from the nasal cavity to the nasopharynx
Upper, middle and lower conchae directs air flow to post nares
Warm because heat from blood vessels is close enough to the wall
Describe the 5 ways that ventilation is controlled
Peripheral and central chemoreceptors Proprioception Irritant/C receptors Stretch receptors Hypothalamus (pain, emotion)
How do peripheral and central chemoreceptors change ventilation
+ve
Conc of gases in blood (PO2, PCO2) altered by increased ventilation rate