The Skeletal System Flashcards
Osteblasts
Cells that form bone, secrete the matrix
The matrix
Intercellular substance
Ossification
The matrix is infiltrated with calcium and phosphate in the form of hydroxyapatite crystals
Hydroxyapatite crystals
Give bone its characteristic hardness
Lacunae
The ossified matrix
Canaliculi
Cellular processes in tiny channels through the bone, osteocytes obtain food and communicate w each other
Functions of bones
Support, protection, leverage, and storage
Two hormones that act as “cashiers” at the calcium bank
Calcitonin (prevents hypercalcemia) and parathyroid hormone (prevents hypocalcemia)
Calciotropic
The hormones are involved in the regulation of calcium levels in the body
Hematopoisesis
Blood cell formation
Two main types of bone
Cancellous bone and compact bone
Cancellous bone
Light and spongy, consists of tiny spicules of bone that appear randomly arranged w lots of spaces btwn them
Compact bone
Heavy and dense, makes up shafts of long bones and the outside layer of all bones. Composed of tiny, tightly compacted cylinders of bone called Haversian systems
Haversian canal
Contains blood vessels, lymph vessels, and nerves that supply the osteocytes
Periosteum
A membrane that covers the outer surfaces of bones
Endosteum
A membrane that lines the hollow interior surfaces of bones
3 type of cells that make up bone:
Osteoblasts, osteocytes, and osteoclasts
Osteocytes
Created once the osteoblast becomes trapped in the ossified matrix
Osteoclasts
Instead of forming bone, they eat it away, also allow the body to withdraw calcium from the bones when necessary
Volkmann’s canals
Tiny channels in the bone matrix, blood vessels here join w the blood vessels in the Haversian canals to bring nutrition to the osteocytes in the Haversian systems
Nutrient foramina
Large blood vessels, along with lymph vessels and nerves,
also enter many large bones, especially long bones, through large channels called nutrient foramina
2 ways bone is formed:
Grows into and replaces a cartilage model (endochondral or cartilage bone formation), or it develops from fibrous tissue membranes (intramembranous or membrane bone formation)
Endochondral bone formation
The body creates a cartilage “template” that is subsequently replaced by bone
Femur
Thigh bone