The Respiratory System Flashcards
Inverse relationship between volume and pressure
Boyle’s Law
- Each gas in a mixture exerts its own pressure
- The pressure of a specific gas in a mixture is its partial pressure
Dalton’s Law
The quantity of a gas that will be dissolved in a liquid is proportional to the partial pressure of the gas and its solubility coefficient
Henry’s Law
The rate of gas transfer is proportional to the tissue area, the diffusion coefficient of gas, and the partial pressure gradient across the tissue and is inversely proportional to the thickness
Fick’s Law
Control of Ventilation
- Mainly controlled by brainstem
- Pneumotaxic centre
- Apneustic centre
- Chemoreceptors
- Peripheral
- Emergency detection for low O2
- Carotid receptors provide rapid response pH/CO2 detection
* Central (brainstem extracellular)
- Steady state control
- Peripheral
- Line airways to end of respiratory bronchioles
- Possess cilia and secrete mucus
- Trap particulates
Airway epithelial cells
- Alveolar squamous epithelial cells
- 1 cell wall forms alveoli structure
Type 1 cells
- Alveolar epithelial cells
- Secrete surfactant
Type 2 cells
- Mobile, phagocytic cells
Alveolar macrophage
Minute Ventilation =
Tidal volume x breathing frequency