The Newborn Infant Flashcards

1
Q

what structure allows foetal bood to bypass the liver, and what vessel does it join into

A

the ductus venosus

joints into the IVC - drains into RA of heart

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2
Q

what structures in the heart allow the blood to bypass the lungs

A
  • the foramen ovale between the RA and LA allows blood to flow straight from RA to LA, then LV and out aorta
  • if any blood escapes the FO and flows into RV and then out pulmonary artery, the patent ductus arteriosus will allow it to enter the aorta
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3
Q

by which gestational age does the foetus have lungs that function well enough (dont need steroids if delivered)

A

36 weeks

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4
Q

when does the baby start producing surfactant, and what does this do

A

from around 24 weeks, it reduces alveolar surface tension stopping the smaller alveoli from collapsing

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5
Q

how does vaginal delivery help lung preparation for the outside world

A

it squeezes the fluid out of the lungs

if eg C section, there will be delayed clearance of lung fluid and transient tachypnoea/resp distress

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6
Q

what are O2 sats expected to be when thebaby is born

A

they will intially be around 70% and will increase to around 90% over teh first 10 minutes

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7
Q

hwat colour is the baby when born

A

blue, turns pink as oxygenated

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8
Q

what changes happen in the lungs after birth

A

the lungs before were a very high pressure system (unfavourable.). PVR drops and SVR rises, driving blood through lungs

FO and DA close

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9
Q

what causes closure of teh FO, and what is left behind

A

the pressure in LA > RA - forcing FO shut

fossa ovalis remains

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10
Q

what kept the DA open in utero, and what now causes it to shut

A

it was kept open by the placental PG

after birth, there are no more PG and high O2 tension causes the smooth muscle in it’s walls to constrict

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11
Q

what is the closed DA called in children/adults

A

ligamentum arteriosum

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12
Q

what murmur would a PDA cause

A

machine like murmur below the left clavicle

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13
Q

how do you manage a PDA

A

IV NSAIDs - indomethacin or ibuprofen (anti COX action inhibits PG production and causes closure).

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14
Q

what does the ducuts venosus become

A

the ligamentum teres (round ligament) in the liver

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15
Q

why are neonates particularly prone to rapid heat loss

A
  • covered in fluid when born
  • have a high surface area : volume ratio
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16
Q

what are the 4 mechanisms by which neonate can lose heat

A
  • radiation
  • evaporation of fluid
  • conductive - contact with cold surface
  • convection - air flow
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17
Q

how do babies warm themselves up? they cant shiver

A
  • non shivering thermogenesis
  • stored brown fat breaks down in response to catecholamines - heat is generated through ATP
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18
Q

where is the brown fat found in babies

A

between scapula, around organs, sternum

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19
Q

does NST work immediately from birth?

A

no, takes around 12 hours

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20
Q

what are the negative consequences of hypothermia, and NST

A

it increases metabolic rate

  • so uses a lot of O2 = resp rate increases to get more O2 = cant meet demands = anaerobic metabolism and hypoxia
  • uses lots of glucose - depletes glycogen stores and results in hypoglycaemia
  • hyopglycaemia leads to decreased surfactant proudction and pulmonary vasoconstriction - resp distress
  • = HYPOXIA
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21
Q

what necessary precuations must be taken to keep baby warm

A

good delivery room temperature, dry baby immediately, swaddle (hat), skin to skin contact

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22
Q

what extra precuations must be taken for premature babies or to rewarm hypothermic babies

A
  • put in polyethene bag
  • blankets/clothes, heated mattress, prewarmed incubator
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23
Q

what is the normal weight range for a newborn baby

A

2.5-4kg

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24
Q

neonatal vital signs

A
  • Resp rate: 40-60, signs of work of breathing may be attributable to circulatory adaptation
  • HR: 120-140
  • Cap refill: 2-3 seconds
  • Colour: Pink/blue/white
  • SaO2: Around 65-70% when born, increase to 90% in first 10 minutes
25
Q

what benefit does crying hav on lung developmen

A

it helps to push fluid out of the lungs

26
Q

what are the benefits of delayed cord clamping

A

better outcome for baby = higher haematocrit, Hb levels, better blood flow to vital organs

avoids anaemia and hypovolaemia

27
Q

when shoudl the cord be cut (delaeyd cord clamping)

A

when it stops pulsating - 30-60 seconds

28
Q

what is a normal Apgar score

A

8/8

29
Q

outline Apgar score

A
30
Q

why is skin to skin recommended s highly

A

it is assoicated with improved bonding and higher breast feeding rates

it keeps the baby warm

31
Q

mother is worried because baby is not feeding much, 18 hours old?

A

wont feed much for first

24 hours - reassure

32
Q

what extra precuations are taken if mother is known to be at high risk of hep B infection

A

baby is given an immediate vaccination instead of waiting for routine one at 2 months

33
Q

what extra precuations are taken if mother is known to have HIV

A

post exposure prophylaxis - drug infusion started within 4 hours of delviery and continued for 4 weeks

combination drug if DVL, monotherapy if UVL

34
Q

what ART drug is used for HIV in babies

A

zidovudine (NRTI)

35
Q

what extra vaccines does the mother during prengancy get to protect the baby

A

pertussis vaccine from 16 weeks gestation and influenza vaccine

36
Q

what NHS intiative has been put in place to keep babies warm and healthy

A

newborn snuggle bundle

37
Q

within what time frame should the newborn physical examination be carried out

A

72 hours

38
Q

what resp rate and heart rate would you expect on examination

A

resp 30-60

heart 100-150

39
Q

if a baby is at high risk of hip problems, what is done

A

US of hips

eg breech birth

40
Q

what 4 things does the heel prick test test for

A

sickle cell

cystic fibrosis

inherited metabolic diseases

congenital hypothyroidism

41
Q

which sleeping position is recommended for baby

A

on back

42
Q

what is the greatest risk factor for neonatal death

A

prematurity

43
Q

does previous preterm births put you at risk of more

A

yes, increases risk a lot

44
Q

LOW ADMISSION TEMPERATURE IS AN INDEPENDENT RISK FACTOR FOR NEONATAL DEATH

A
  • low BMI, minimual muscle activity
  • less brown fat
  • les subcutaenous fat
  • large surface area : volume ratio
45
Q

the premature baby has an increased risk of nutritional compromise, how is this managed?

A

parenteral nutrition initially

46
Q

what is hypoxic ischaemic encephalopathy

A

brain and organ damage that occurs due to hypoxia, range in severity

47
Q

how will the baby with HIE present

A

signs of hypoxia and low Apgar score at birth

later in lfie it will have developmental delay, epilepsy, cognitive issues etc

48
Q

management of HIE

A

active resuscitation

cooling treatment - this changes chemical processes in the brain so that less damage is done. can use cooling mat

49
Q

what glucose concentrations are considered to be hypoglycaemia in term and preterm infants

A

<2.2 and <1.7 respectively

50
Q

what commonyl causes transient hypoglycaemia in babies

A

LBW/premature - dont have enough glycogen stores.

51
Q

which drug that is used in obstetric management can cause transienet hypoglycaemia in baby

A

labetalol

52
Q

why will the baby of a diabetic mother be hypoglycameia

A

in order to adapt to high blood glucose levels from mother baby pancreas beta cells undergo hyperplasia - hyperinsulinaemia

53
Q

how does a hypoglycaemic baby present

A

many asymptomatic

sweating, tachycardia, lethargy, neurological signs

54
Q

management of hypoglycaemic baby

A

IV/gel dextrose

55
Q

what is the cause of most early onset neonatal ifnections

A

tend to be acquired intrapartum - most are group B strep

56
Q

what are TORCH infections

A

ones that are known to produce congenital defects

toxoplasmoa, others, rubella, CMV, herpes/hepatitis

57
Q

when would you screen for GBS?

A

no screening even on maternal request

58
Q

managment of GBS

A

benzylpenicillin ABx

59
Q
A