The Nervous System Flashcards
Soma
Cell body of neuron, location of nucleus and ribosomes
Dendrites
Appendages from soma that receive incoming messages from other cells
Axon hillock
Integrates incoming signals, transmits action potentials (transmission of electrical impulses down axon), sums up all signals (excitatory and/or inhibitory) and yields action potential if sum is excitatory
Myelin
Fatty membrane that insulates nerve fibers to prevent signal loss, crossing of signals, and speed of conduction in axon
What produces myelin?
Oligodendrocytes (central nervous system) and Schwann cells (peripheral nervous system)
Nodes of Ranvier
Small breaks in myelin sheath with exposed areas of axon membrane, used for rapid signal conduction
Nerve terminal or synaptic bouton (knob)
Flattened end of axon to maximize transmission of signal to next neuron and releases neurotransmitters
Demyelination
Destruction of myelin as a result of immune response, slowing down information transfer (one disorder is multiple sclerosis)
Synaptic cleft
Small space into which terminal portion of axon from presynaptic neuron release neurotransmitters to dendrites of adjacent (postsynaptic) neuron
Synapse
Consists of nerve terminal, synaptic cleft, and postsynaptic membrane
Nerve
Bundle of multiple neurons in peripheral nervous system, can be sensory, motor, or mixed
Ganglia
Cluster of cell bodies of neurons of same type in peripheral nervous system
Tract
Bundle of axons in central nervous system, can only carry one type of information
Nuclei
Bundle of cell bodies of neurons in same tract in central nervous system
Astrocytes
Form blood-brain barrier
Ependymal cells
Line ventricles of brain and produce cerebrospinal fluid, a shock absorber
Microglia
Phagocytic cells that break down waste products and pathogens in CNS
List of all glial cells
Astrocytes, ependymal cells, microglia, oligodendrocytes (CNS), Schwann cells (PNS)
Resting membrane potential
Net electric potential difference that exists across cell membrane (-70 mV in neurons), generated and maintained by potassium and sodium ions, closer to potassium’s equilibrium potential as cell is slightly more permeable to potassium
Potassium leak channels
Allow for slow leak of potassium out of cell in this favorable direction due to potassium concentration inside cell being 140 mM compared to 4 mM outside cell, leaving behind small amount of negative charge and making outside slightly positively charged
Equilibrium potential of potassium
Around -90 mV, negative sign is due to positive potassium ion leaving the cell