The membrane bilayer: Structure Flashcards
what is the function of biological membranes
1) Continuous,highly selective permeability barrier
2) control of the enclosed chemical environment
3) communication
4) recognition of signalling molecules
5) signal generation in response to stimuli
by dry weight what is the membrane composed of ?
60% protein
40% lipid
1-10% carbohydrate
membrane are hydrated structures so how much water do they contain
20%
describe the structure of a phospholipid
glycerol backbone attached to phosphate and head group(small)
glycerol backbone is attached to fatty acid tails
name some phospholipid heads
choline
serine
ethanolamine
inositol
what is a sphingolipid
lipid found in membrane
doesn’t have a glycerol backbone
synthesised by bringing together a fatty acid chain and sphingosine molecule
how can glycolipids be classed
cerebroside (glycolipid with single monosaccharide head grp) and gangliosides(glycolipid with disaccharide head grp)
role of cerebrosides
determine major blood groups
role of gangliosides
important for function in CNS and are used by particles for invasion (cholera,flu)
describe the structure of cholesterol
hydrophobic tail made up of 4 steroid rings. steroid ri nags are connected to a short 8 carbon tail. the hydrophilic head is a single hydroxy -OH group coming off the uppermost ring
describe the lipid bilayer
a sea of lipid stabilised by interaction with H2O through hydrophilic heads and stabilisation of structure by hydrophobic interaction of the tails