The IPAC Program Flashcards
define a toxoid
a modified bacterial toxin capable of stimulating antitoxin formation
True or false. Passive immunization is effective, but protection is generally limited and diminishes over time (usually a few weeks or months)
true
what is an immunoglubonulin
sterile solution containing antibodies from human blood
what is an antitoxin
a solution of antibodies derived from the serum of animals immunized with specific antigens
true or false. immunization is a broader term that encompasses the use of any immunobiologic to prevent infectious diseases by inducing immunity
true
what are some whole-cell inactivated vaccines?
polio
HAV
rabies
what are some inactive recombinant vaccines?
HBV and HPV
Vaccines can be described as monovalent (a single strain or type of organism), trivalent (three types or strains of a single organism or three different organisms), quadrivalent (four influenza strains), or polyvalent (multiple strains or types
true
what are some potential vaccine allergens?
-stabilizers
-preservatives
-animal proteins
-antibiotics
the only vaccine virus that has been isolated in breast milk is
rubella
what is a precaution
a condition in a potential vaccine recipient that may increase risk of a serious adverse event or comprimise the ability of the vaccine to produce immunity.
what are some examples of precautions?
-moderate or severe acute illness with or without fever
-pregnancy
-previous history of guillian-barre syndrome
-immunosupression
-receipt of an antibody-containing product within a certain time period of vaccination
in who should live vaccines be avoided?
malignancy, symptomatic HIV infection, treatment-induced immune suppression, and similar conditions
exception: MMR in asymptomatic HIV patients
true or false. Inactivated vaccines are not problematic in immunocompetent persons
true
true or false. patients with a mild acute illnesses accompanied by a low-grade fever and recent exposure to an infectious disease are not contraindicated for immunization if they are otherwise healthy
true
who is the dengue fever vaccine recommended for?
anyone ages 9-16 who has had the disease and lives in an endemic area. Not for travelers. Do not vaccinate anyone who has not had dengue as it puts them at risk for severe disease. the second infection poses the highest risk of severe disease
describe vaccine recommendations for Hib (haemophilus Influenza B)
-infants starting at 2 months should get a 2-3 dose monovalent series. booster dose at 12-15 months. not recommended above age 59. Can cause immunobiologic intolerance if administered at under 6 weeks old
who is HAV vaccine recommended for?
adults with chronic liver disease, MSM, international travellers, drug users
not licensed as post exposure prophylaxis
is history of GBS a conctraindication for HBV vaccination?
No
at what age is HPV vaccine given?
females ages 11-12. As young as 9 if victims of sexual assault. catch up vaccination recommended up until age 26. no maximum interval between doses. Infection generally occurs after first sexual experience.
who should get the rotavirus vaccine?
infants. there are 2 live oral vaccines. max age to be given is 14 weeks 6 days. 4 weeks between doses
why are standing orders good?
improve rate of vaccination
what 3 areas must HCP be trained in to give vaccines under a standing order?
-administering vaccine
-contraindications
-adverse events
who is meningitis vaccine recommended for?
any aged up to 55 years. HCP that may be exposed. Two doses of under 16 and one if above.