Dialysis Flashcards
What is peritoneal dialysis?
-the removal of toxins, electrolytes, and fluid by diffusion through the peritoneal membrane.
-requires placement of catheter into perotneal cavity.
-can be continuous ambulatory peritoneal dialysis, intermittent peritoneal dialysis, or continuous cycling peritoneal dialysis
What are some types of infections caused by peritoneal dialysis (hint: there are 3)
- exit site infection
- subcutaneous tunnel infections
- peritonitis
what are some risk factors for peritoneal dialysis infections?
-young age
-staph nasal carriage
-lack of compliance with routine procedures (poor exit site care, break in aseptic procedures)
-dialysate leak
-exit site breakdown or poor healing
-trauma to the exit site
-dislodging of the catheter cuff
what pathogens most commonly cause exit site infections with peritoneal dialysis?
staphlococci and pseudomonas
what pathogens most commonly cause subcuteanoues tunnel infections with peritoneal dialysis?
S. aureus, P. aurginosa, and enterobacteriaceae
what pathogens most commonly cause peritonitis with peritoneal dialysis infections?
coagulase-negative staph, s. sureus, and streptococci
what are signs and symptoms of an exit site infection?
erythmea, tenderness, exuberant granulation tissue, exit site with purulent and/or bloody drainage
what are signs and symptoms of a subcutaneous tunnel infection?
weythmea, edema, or tenderness of the subcutaneous catheter pathway with purulent drainage or cellulitis
what are signs and symptoms of peritonitis?
at least two of the following: S & S of peritonitis (abdominal pain or fever), cloudy dialysate with white blood cell counts >100 cells/mm3 and 50 polymorphonuclear leukocytes, positive culture, or gram’s stain of the dialysate
what are some steps to reduce peritoneal dialysis related infections?
-proper catheter placement (avoid skin folds, beltline)
-use of a double cuff catheter
-catheter should be placed under sterile conditions in the OR
-proper exit site care of the operative wound and after healing
-being vigilant for early manifestations of infection
what does hemodialysis do?
removes toxins, electrolytes, and fluid by circulating the patients blood through a hemodialyzer
-requires a vascular access
-usually a 3-4 hour treatment 3x a week and can be done in center or at home
what are 3 types of hemodialysis vascular access (in order of lowest to highest risk of infection)?
- arterio-venous fistula (AVF)
- arterio-venous graft (AVG)
- tunneled, cuffed venous catheter (if catheter is used for more than 3 weeks) or non cuffed catheter for acute hemodialysis less than 3 weeks duration
what is AVF?
a surgical creation of anastomosis (connection) between an artry and vein
-causes arterialized blood to flow through the vessel
-results in enforgement and enlargement of the vessel
-lowest risk of infectino
what is an arteriovenous graft?
-synthetic material is interposed between an artery and vein
-expanded polytetrafluoroethylene/Teflon
-composite/polyurethane
risk of infection from AVF and AVG may result from what?
-break in aseptic technique
-bacterial seeding from another part of the body
-poor hygiene and care of access site
-added risk with AVG is disintegration of graft materials and hemorrhage
how do you lower risk of infection with AVF and AVG?
-clean technique with clean barriers and gloves and attention to aseptic technique
-arm should be cleaned with antibactrial soap or scrub with water
-2% chlorhexidine gluconate is the antimicrobial of choice
where does a tunnelled, cuffed CVC get placed and what are indications for use?
-placed within right atrium
-indications are long term access (>3 weeks duration)
where does a non-cuffed CVC get placed and what are indications for use?
-superior vena cava
-short term or acute dialysis only less than 3 weeks
-use of femoral vein has the highest risk of infection
What is the most common bacterial cause of vascular access site infections?
staphlococcus aureus
the majority of CVC bloodstream infections in hemodialysis patients are caused by what organisms?
gram positive (coagulase-negative staph and s.aureus)
-usually related to access site care
-can be caused by water associated gram negative organisms (stenotrophamonas, serratia, pseudomonas)
what is the preferred antiseptic that should be used to clean the dialysis catheter exit site?
2% chlohexidine gluconate