The inflammation response Flashcards
Describe inflammation
one of the body’s nonspecific defense
- localized, tissue- level response to any injury or infection- not systemic
-produces indications of injury
Describe 4 cardinal signs of injury
- tumor- swelling
- rubor- redness
- calor- warmth
- dolor- pain
Define lysosomes
organelles that contain lysosomal enzymes;
provide an isolated environment for potentially dangerous chemical reactions
Define lysosomal enzymes
break down biological materials (damaged organelles, bacteria, debris etc.)
Describe the first step of the process of inflammation
- After injury, damaged cells spill their contents into the surrounding tissues including lysosomal enzymes which cause further damage by destroying tissue in localized area
define necrosis
cell death
describe the second step of the inflammation process
mast cells are stimulated (based off damaged cell & necrosis) and releases chemicals (histamines, herpains etc.)
define pus
dying cells, damaged fibers,, cell parts, debris, etc
define abscesss
pus in an enclose tissue space
How do mast cell chemicals cause inflammation?
- cause blood vessels to dilate (redness and warmth0–> more blood flow
- increase vessel permeability- more fluid and interstitial fluid leaves than normal –> swelling
- stimulate sensory nerve endings –> pain
swelling= tissue stretches= pain
How does the body pay extra attention to the inflamed area?
extra nutrients & O2; WBC’s to fight infections & clean up dead material
When does regeneration occur?
when injury or infection is cleaned up, healing
How is scar tissue formed?
fibroblasts move into necrotic areas & lay down collagen fibers, creating it so it can bind the area together
- depth determines if a scar is formed
Do all tissues regenerate equally?
NO
What are some examples of tissues that regenerate well?
epithelia, CT (except cartilage) & smooth muscle
