The Immune Response 201 Flashcards
What is the body’s coordinated reaction to components of microbes, macromolecules and substances that the body recognizes as foreign, regardless of whether the response has helpful or harmful consequences?
Immune Response
What is the rapid, nonspecifics response the body mounts against foreign invaders?
Innate Immune Responsed
Which cells have the ability to engage in Phagocytosis?
- Neutrophils
- monocytes
- Macrophages
What are the white blood cells that originate from a single pluripotent hematopoietic stem cell type in bone marrow?
Leukocytes—Phagocytosis and other immune responses are mediated by leukocytes
What are the two categories of Leukocytes?
- Granulocytes (ganular)
2. Mononuclear (non-granular)
What are the 4 Granulocytes?
- Neutrophils
- Eosinophils
- Basophils
- Mast Cells
Which granular leukocytes are the most abundant circulating white blood cells and are rapidly recruited to inflammatory sites?
Neutrophils
Which Granular Leukocytes defend the body by extruding proteins to which bacteria can stick, forming “traps” which assist with the immobility on of these invaders and their removal from the body?
Neutrophils
Which Granular Leukocyte plays a role in protecting the body against large parasites?
Eosinophils
Which of the Granular Leukocytes are the rarest type of white blood cells that release histamine?
Basophils
Which white blood cells are considered Mononuclear (non-granular) cells?
- Monocytes
- Macrophage
- Dendritic Cells - Lymphocytes
B cells T cells NK Cells
Which of the Agranular Leukoctyes are the largest white blood cells? These cells can enter tissues and differentiate into macrophages and have a half life of 1-3 days.
Monocytes
Which of the Mononuclear white blood cells rid the body of bacteria by the process of phagocytosis?
Macrophages
Which of the Mononuclear cells have both innate and adaptive immune functions and are an important bridge linking these two forms of immunity?
Dendritic Cells
Which of the Mononuclear cells are present in the epithelial tissue as well as other tissues in the body and because of their location can act as “Sentinels” to detect invading microbes.
Dendritic Cells—-
- They are the body’s most versatile sensors of pathogens and damaged cells.
What are the 3 classes of Lymphocytes?
- B cells
- T cells
- NK cells
Which Lymphocytic cells can recognize patterns characteristic of damaged or infected cells and kill these cells directly thru apoptosis—or to self destruct.
NK Cells
- Considered the Ninja of the Immune System.
Once cells are infected, they are typically damaged beyond repair. But they can secrete
___________ to protect surrounding cells from becoming infected.
Interferons
- So named because they “interfere” with viral infection in several ways.
Which of the following red the body of bacteria, other infectious particles, worn out cells, and other debris by the process of phagocytosis?
Macrophages
Complement proteins work to enhance the process of______________?
Inflammation
Synovial inflammation, called synovitis, occurs when__________ infiltrates the synovial compartment
Leukocytes.
What are the large molecules that the body recognizes as foreign, such as bacteria, viruses, molds, or parasitic worms?
Antigens
What are the portions of Antigens that are specifically recognized by lymphocytes?k
Epitopes
What are the 2 types of Lymphocytes?
- B cells
2. T cells
Which Lymphocytes are antibody-producing cells responsible for humoral immunity?
B Cells
Which Lymphocytes are non-antibody-producing cells responsible for cellular immunity?
T Cells