The Heart as a Pump Flashcards

1
Q

How does pulmonary arterial pressure differ from systemic pressure?

A

It’s lower as TVR in pulmonary vascular bed is much lower –> less pressure needed from R side to push same CO through pulmonary circuit

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2
Q

Why is it important that both pulmonary and systemic circuits have the same cardiac output?

A

Blood would gradually accumulate in one side of heart

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3
Q

How is blood flow calculated?

A

Flow = pressure/resistance (for both circuits separately)

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4
Q

What is the tricuspid valve?

A

Right AV valve

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5
Q

What is the bicuspid/mitral valve?

A

Left AV valve

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6
Q

What is the pulmonary valve?

A

Semilunar valve between right ventricle and pulmonary artery

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7
Q

What is the aortic valve?

A

Semilunar valve between the left ventricle and the aorta

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8
Q

What is the role of papillary muscles?

A

First to contract in ventricular systole to pull chordae tendinae to close valves

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9
Q

What are ‘chordae tendinae’?

A

Fibrous tendons which attach to valves to keep them in position (also attached to papillary muscles)

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10
Q

Describe the valve sequence of the left side of the heart in a normal cardiac cycle

A

Start of systole - left ventricle starts to contract so mitral/bicuspid valve closes
During systole - pressure increase causes aortic valve to open
End of systole - aortic valve closes
Pressure near zero - mitral valve reopens

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11
Q

How are ventricles usually filled?

A

As a result of the elastic recoil of ventricular wall during diastole

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12
Q

What causes heart sounds?

A

Turbulent blood flow either due to normal valve closure or pathology of valves

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13
Q

Describe the ‘lubb’/S1 heart sound

A

Due to closure of AV valves followed by opening of semilunar valves

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14
Q

Describe the ‘dupp’/S2 heart sound

A

Closure of semilunar valves followed by opening of AV valves

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15
Q

Describe the S3 heart sound

A

Faint, low-pitched sound and can be indicative of serious heart damage in adults, but is relatively common in children and young adults

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16
Q

Where would you auscultate the aortic semilunar valve?

A

Left of sternum at 2nd intercostal space

17
Q

Where would you auscultate the pulmonary semilunar valve?

A

Right of sternum at 2nd intercostal space

18
Q

Where would you auscultate the bicuspid/mitral valve?

A

Mid-axillary line of the 5th intercostal space

19
Q

Where would you auscultate the tricuspid valve?

A

Just to right of sternum at bottom of 5th intercostal space

20
Q

State Starling’s law

A

Ventricular contractile force increase with increased end diastolic volume

21
Q

Explain Starling’s law

A

Increase in preload (blood delivered to ventricles) causes greater dilation of ventricular walls (due to greater EDV) and therefore greater recoil –> greater force of contraction –> greater SV –> greater CO

22
Q

When does Starling’s law fail?

A

If ventricle expands beyond certain volume the ventricles become overstretched and weaken (heart failure)

23
Q

Define ‘preload’

A

Degree of stretching of ventricle during diastole

24
Q

Define ‘afterload’

A

The effective flow impedence/resistance of the aorta and large arteries

25
What mediated venous return to the heart?
One-way valves, muscular pumps (contraction of muscle --> propels blood), thoraco-abdominal pump
26
What causes JVP?
When right atrium contracts, backpressure occurs (due to absence of valves) in the jugular vein which can be felt as feint pulse
27
What is preload proportional to?
End diastolic volume
28
What is the consequence of a large afterload?
Causes longer period of ventricular systole before semilunar valves open, and shorter ejection duration --> smaller SV and larger residual volume
29
What is the thoraco-abdominal pump?
In inspiration; thoracic cavity pressure reduces --> pulls blood into IVC Expiration; thoracic pressure increases and blood is forced into right atrium