the hardy- weinberg equation pack 9 Flashcards
allele frequencies equation
p + q = 1
p =
frequency of the dominant allele
q =
frequency of the recessive allele
hardy - weinberg equation
p^2 + 2pq + q^2 = 1
the hardy- weinberg principle states that allele frequencies don’t change from one generation to the next assuming:
- the population size is large enough for genetic drift not to occur
- mating is random
- there’s no gene flow -> the population is isolated
- no mutations / mutations are rare
- no natural selection
if any of these conditions aren’t met a change in allele frequencies can occur
the hardy - weinberg equation can be used to see whether there
has been a change in allele frequencies over time. this can be done by comparing the allele frequencies at two points in time. if they have changed, this indicates that evolution has occurred
how to use the hardy - weinberg equation
1) calculate the frequency of homozygous recessive individuals in the population, q^2 - divide the number of individuals with that genotype by the total number of individuals in the population
2) calculate the frequency of the recessive allele, q - square root of q^2
3) calculate the frequency of the dominant allele, p- 1-q
4) calculate the frequency of homozygous dominant individuals, p^2- p x p
5) calculate the frequency of heterozygous individuals, 2pq- 2 x p x q
q^2 =
homozygous recessive
how to calculate q^2
total number of homozygous recessive / total number of organisms
heterozygous allele =
2pq