The Eye (Martin) Flashcards

1
Q

What is an important clinical manifestation of Graves disease?

The pathogenesis of the phenomenon is due to?

A

1) Axial proptosis (exophthalmos)

2) Increase in glycosaminoglycans

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2
Q

What is the most common malignancy of the eyelid?

A

Basal Cell Carcinoma

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3
Q

How are basal cell carcinomas described?

A

Pearly with a depressed central area

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4
Q

What can cause unilateral keratoconjunctivitis unresponsive to therapy (masquerade syndrome)?

A

Sebaceous carcinoma

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5
Q

What are submucosal elevation of the conjunctiva?

What are small, yellowish submucosal elevation of the conjunctiva?

What do they result from?

Which does not invade the cornea?

A

1) Pterygium
2) Pinguecula
3) Sun exposure (actinic damage)
4) Pinguecula

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6
Q

What is the most common intraocular tumor in adults?

It is associated with mutations in?

A

1) Uveal melanoma

2) GNAQ and GNA11

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7
Q

Uveal melanoma has a worse prognosis if?

A

Epithelioid cells are present

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8
Q

What contributes to the corneas lack of rejection to transplantation?

A

The corneal stroma lacks blood vessels and lymphatics

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9
Q

What are lenticular opacities that can be congenital or acquired?

A

Cataracts

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10
Q

What is one of the biggest risk factors for cataracts?

A

Diabetes mellitus

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11
Q

Phagocytic glaucoma is a form of?

A

Secondary, open-angle glaucoma

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12
Q

What is morgagnin cataract in regards to phagocytic glaucoma?

A

When the lens cortex may liquefy nearly entirely

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13
Q

Glaucoma is mostly assocaited with?

A

Increase in intraocular pressure

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14
Q

What is the most common primary intraocular malignancy in kids?

A

Retinoblastoma

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15
Q

What is the most common symptom of retinoblastoma?

Prognosis becomes worse if there is extraocular extension and invasion along the?

A

1) Leukocoria (white pupillary reflex)

2) Optic nerve

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16
Q

In regards to retinoblastoma, what is pseudohypopyon?

A

When the cells shed into anterior chamber and aggregate to form nodule on iris

17
Q

In differentiated Retinoblastoma tumors what are there that reflect photoreceptor differentiation?

A

Flexner-Wintersteiner Rosettes and Fleurettes