The Endocrine System Flashcards
Second controlling system of the body
Endocrine System
fast-control system
Nervous system
Uses chemical messengers that are released into the blood
hormones
• Hormones control several major processes
• Reproduction
• Growth and development
• Mobilization of body defenses
• Maintenance of much of homeostasis
• Regulation of metabolism
are produced by specialized cells
Hormones
Secrete hormones into extracellular fluids
Cells
transfers hormones to target sites
Blood
scientific study of hormones and endocrine organs
Endocrinology
Hormones are classified chemically as
Amino acid-based
Steroids
Prostaglandins
Amino acid-based, which includes:
• Proteins
• Peptides
• Amines
made from cholesterol
Steroids
made from highly active lipids that act as local hormones
Prostaglandins
Hormones affect only certain
tissues or organs (target cells or target organs)
must have specific protein receptors
Target cells
arouse cells or alter cellular activity
Hormones
alters cellular activity
Hormone binding
Hormones act by two mechanisms
Direct gene activation and Second-messenger system
Used by steroid
hormones and thyroid hormone
Direct gene activation
Used by protein and peptide hormones
Second-messenger system
The stimuli that activate endocrine glands fall into three major categories
- Hormonal 2. Humoral 3. Neural
Most common category of stimulus
Hormonal stimuli
are activated by other hormones
Endocrine organs
Endocrine organs are activated by other hormones
Hormonal stimuli
Hormones of the hypothalamus stimulate the anterior pituitary to secrete its hormones
Hormonal stimuli
Changing blood levels of certain ions and nutrients stimulate hormone release
Humoral stimuli
indicates various body fluids. such as blood and bile
Humoral
Humoral indicates various body fluids. such as blood and bile
Humoral stimuli
Humoral indicates various body fluids such as
blood and bile
produced in response to changing levels of blood calcium levels
Parathyroid hormone and calcitonin
Parathyroid hormone and calcitonin are produced in response to changing levels of blood calcium levels
Humoral stimuli
is produced in response to changing levels of blood glucose levels
Insulin
Insulin is produced in response to changing levels of blood glucose levels
Humoral stimuli
Most are under the control of the sympathetic nervous system
Neural stimuli
stimulate hormone release
Nerve fibers
Nerve fibers stimulate hormone release
Neural stimuli
Sympathetic stimulation of the adrenal medulla to release epinephrine and norepinephrine
Neural stimuli
The Major Endocrine Organs
• Hypothalamus
• Pituitary gland
• Pineal gland
• Thyroid gland
• Parathyroid glands
• Thymus
• Adrenal glands • Pancreas
• Gonads (testes and ovaries)
are ductless glands
Endocrine glands
are released directly into blood or lymph
Hormones
Hormones are released directly into
blood or lymph
Pea-sized gland that hangs by a stalk from the hypothalamus in the brain
Pituitary gland
Pituitary gland is protected by the ____ of the ____
sella turcica of the sphenoid bone
Protected by the sella turcica of the sphenoid bone
Pituitary gland
Pituitary gland has two functional lobes
Anterior pituitary and Posterior pituitary
Anterior pituitary
glandular tissue
Posterior pituitary
nervous tissue
often called the “master endocrine gland” because it controls activities of so many other endocrine glands
Pituitary gland
Hypothalamus also makes two hormones
oxytocin and antidiuretic hormone
Does not make the hormones it releases Stores hormones made by the hypothalamus
Posterior pituitary
Two hormones released
- Oxytocin
- Antidiuretic hormone (ADH)
Only released in significant amounts during childbirth and nursing
Oxytocin
Stimulates contractions of the uterus during labor. sexual relations, and breastfeeding
Oxytocin
Causes milk ejection (let-down reflex) in a nursing woman
Oxytocin
Inhibits urine production (diuresis) by promoting water reabsorption by the kidneys
Antidiuretic hormone (ADH)
Two hormones affect nonendocrine targets
- Growth hormone 2. Prolactin
stimulate other endocrine glands to release hormones
tropic hormone
Four are tropic hormones
Follicle-stimulating hormone
Luteinizing hormone
Thyrotropic hormone
Adrenocorticotropic hormone
General metabolic hormone
Growth hormone (GH)
Major effects are directed to growth of skeletal muscles and long bones
Growth hormone (GH)
Plays a role in determining final body size
Growth hormone (GH)
Causes amino acids to be built into proteins
Growth hormone (GH)
Causes fats to be broken down for a source of energy
Growth hormone (GH)
Stimulates and maintains milk production following childbirth
Prolactin (PRL)
Function in males is unknown
Prolactin (PRL)