The Endocrine System Flashcards
What are the two main types of feedback loops. Explain
Positive (stimulus enhanced)
Negative (stimulus removed)
4 components of feedback systems
- Stimulus
- Receptors
- Regulator (usually the brain)
- Effectors
Definition of homeostasis
Maintaining a constant internal environment despite changes in external environment
Name stimulus for the release of insulin
High blood glucose levels
Name of stimulus for release of glucagon
Low blood glucose levels
How can hormones regulate internal body temp
Thyroxine can change metabolism
Positive feedback and example
Birth, want it to keep going/amplifying it
What are endocrine secretions
When it’s released directly into bloodstream
What is exocrine secretions
When it’s released into a cavity or a chamber
Definition of hormone
Chemical that is secreted by cells in one part of the body Wich is transported to other body parts where it affects particular cells
2 main classes of hormones based on chemical structure
- Steroid
- Protein
What is a steroid hormone
Fat soluble. Example: sex hormones like testosterone and estrogen
Protein hormone
Water soluble, insulin, growth hormone and ADH
Two terms used when abnormal quantities or hormones are released
Hyposecretion (not enough) and hypersecretion (too much)
Steroid hormones, explain how they enter and work
They diffuse into membrane, then forms the hormone-receptor complex. Then this diffuses into the nucleus and attaches to DNA.
How do protein hormones enter and work
They bind to specific receptors, this activated enzymes to convert ATP into cyclic AMP
What is cyclic AMP
Forms from ATP after the protein hormon binds to receptor
What is a hormone
Chemical messenger
What is an antagonistic hormone
Keeps body in homeostasis, does smt then other does opposite. Example: insulin and glucagon
What are the two structures that make the nervous system and endocrine system interact
Hypothalamus and pituitary gland
What does the hypothalamus do
Regulates the secretion of pituitary gland
The two hormones for posterior pituitary gland and their targets
- Oxytocin targets mammory glands and uterus
- ADH targets kidney (distal tubule)
What is ADH, where is ADH made and stored
It’s the antidiuretic hormone, made is hypothalamus and stored in posterior pituitary gland
When is ADH released
When nerve impulse reach hypothalamus Wich tells the posterior pituitary gland to release ADH into blood
What part of the kidney nephron help reabsorbe water
Distal convoluted tubule (DCT)
What is the function of ADH
Conserve body water by reducing urine output and making tubule more permeable to water therefore water leaves and goes to blood
Disease associated with ADH
Diabetes insipidus (low ADH so no reabsorption of water)
What detects the body’s water needs and where is it?
Detected by the osmoreceptor in the hypothalamus
What is a diuretic and two examples
Coffee and alcohol, suppresses the secreation of ADH (no water reabsorption=lots of peeing)
What is the hormone of the anterior pituitary gland that increases metabolic rate and lowers blood sugars
TSH (thyroid stimulating hormone)
What is the target of TSH (thyroid stimulating hormone) and it’s function
Target: thyroid gland
Function: stimulates thyroid gland to secrete hormone called thyroxin Wich increases metabolism