The Endocrine system Flashcards
What is the endocrine system for?
Slow communication via the endocrine system which releases hormones
Fast communication through the nervous system which release neurotransmitters
What is a hormone?
Messenger produced by endocrine cells
secreted into blood via interstitual fluid
Purprose to stimualte specfic cells or tissues into action
Primary endocrine glands
Hypothalamus and pituraity gland Pineal gland Thyroid gland Thymus Adrenal gland Pancreas Gonads
Secondary endocrine organs
Heart Stomach Liver Kidney Small intestine Skin
Types of hormones
Peptide hormones
Steroid hormones
Derivatives of specfic amino acids
Synthesis of peptide hormones
Often synthesized as preprohormones
Cleaved to form prohormones
Prohormones packaged into secretory vesicles by Golgi
Synthesis of steroid hromones
Derived from cholesterol
Cholsterol derived from LDL entering cells via LDL/ recpetors complex
Cholesterol converted to steroid in mitchondria and SER
mitchondrial enzyme
Control of hormone secretion
Ions or nutrinets - humoral stimuli
Neurotranmitters - neural stimuli
Hormones - hormonal stimuli
Hypothalamus
Speciliazed neuron clusters called neuroseceretory cells in the hypothalamus produce the hormones Antiduretic hormone and Oxytocin and transport them to the pituarity
Hromones of the posterior pituitary
Antiduretic hormone
Oxytocin
Pineal gland
Glandular tissue in the brain
Secretes melatonin
Hormones of the thyroid gland
T4: Tetraiodothyronine (thyroxine) – most abundant (90%)
T3: Tri-iodothyronine – not as much made (10%)