The Earth BioGenome Project

Question 1

other similar projects

Answer 1

‘barcode of life’- trying to get smaller sequences from all animals, easier to do as you can barcode from stuff like footprints, faeces

Question 2

current best practice genome sequencing

Answer 2

PacBio Hifi- longish-read, high accuracy, cheaper than regular PacBio

Hi-C is also potentially useful

Question 3

3 benefits of BGP

Answer 3

understanding genomes and evolution
conservation
benefits- drugs, industrial products, pest control etc

Question 4

5 issues

Answer 4

cost- ets. 4.5ish billion?

finding everything

data management- need a lot of samples, need big databases etc

ethics, compliance, bio-piracy- Nagoya protocol

controversial? is it worth investing in, could stuff be wrong (things are getting better so shouldn’t be a big issue)

Question 5

DToL

Answer 5

Darwin Tree of Life- pilot study, attempting to categorise every UK species- testing out ideas (e.g. should you sample a place at a time or look for a thing at a time, figuring out best methods for storing things/data analysis, no real ethical issues apart from crediting whoever found the sample)