Human population genomics Flashcards
1
Q
where does OOAH suggest humans emerged
A
Ethiopia
2
Q
where did early British populations seem to have emerged from
A
Greek/Turkish darmers, gene flow from this source into British Isles
3
Q
lactase persistence genes
A
LCT = lactase
MCM6 = regulatory region which is altered in lactose tolerant populations
4
Q
height- how many SNPs explaining how much variation
A
12% variation explained by 18 SNPs
5
Q
lactase persistence selection coefficient
A
6%
6
Q
altitude mutation and in what pop
A
EPAS1 in Tibetans
- bonus- seems to be Denisovian
7
Q
niche human traits useful to study
A
altitude tolerance (Tibet)
pygmy phenotypes (Phillipines, some places in Africa)
sickle cell trait (Africa mostly)
MHC types (everywhere)
high-fat diets (Arctic)
