The Drug Discovery Process Flashcards
1
Q
Collaboration among scientists from the academe, industry and government
Done in the laboratory
Molecular biology
A
Discovery
2
Q
A PHYSIOLOGICAL BINDING SITE
A
Target
3
Q
Example of a target
A
Protein
DNA
mRNA
Enzyme
4
Q
Target INTERACTS with a
A
Hit compound
5
Q
NCE/NME/NBE
Synthetic analogs
A
Hit compounds
6
Q
DRUGGABLE small molecule
A
Lead compounds
7
Q
Suitable for pre-clinical and clinical trials
A
Clinical candidate
8
Q
Target is an __________ in the disease mechanism
A
Identified or validated role in the disease
