The Digestive System - LO6 Flashcards

1
Q

what is digestion?

A

breakdown of large molecules through chemical and mechanical processes

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2
Q

what is the digestive system?

A

a series of hollow organs joined in a long twisting tube from mouth to anus - aids food turning into energy and nourishing cells

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3
Q

what are the functions of the mouth in digestion?

A

mechanical - teeth and tongue
chemical - saliva containing enzymes like amylase

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4
Q

what are the components of saliva?

A
  • 90% water
  • enzymes (amylase)
  • mineral ions
  • mucus
  • lysozymes
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5
Q

what does the oesophagus play in digestion?

A

facilitates mechanical and muscular digestion, transporting food from mouth to stomach through peristalsis

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6
Q

describe the digestion process in the stomach

A

churning and mixing food with gastric juice and HCL, aided by contractions, leading to the partial breakdown of proteins

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7
Q

what is the function of the small intestine?

A

primary site of chemical digestion and absorption of nutrients, aided by villi and microvilli

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8
Q

name enzymes present in the villi and their functions

A
  • maltase ( breaks down maltose to glucose)
  • trypsin (breaks down peptides to amino acid)
  • lipase (breaks down fats into fatty acids and glycerol)
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9
Q

what is the role of CCK in digestion?

A

a hormone - released by small intestine to stimulate contraction of gall bladder and release of pancreatic juices

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10
Q

what are the main cell types of gastric glands and their functions?

A
  • zymogenic ( peptic/chief cells) - secrete pepsinogen
  • parietal cells - secrete HCL and mucus
  • enteroendocrine cells- secrete gastrin
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11
Q

what are the components of villi in the small intestine?

A
  • capillary network
  • lacteal
  • intestinal glands
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12
Q

what is bile and what are its functions?

A

bile is produced by hepatocytes and aids in emulsifying fats and digestion by lipase production

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13
Q

what are the functions of the liver?

A
  • synthesises bile salts
  • proteins
  • converts excess glucose to glycogen
  • synthesises urea
  • breaks down Hb
  • stores fats
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14
Q

describe the phases of gastric secretion

A
  • cephalic phase
  • gastric phase
  • intestinal phase
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15
Q

what is phase 1 of gastric secretion?

A

cephalic phase
- initiated by sensory stimuli like sight, smell, taste, or thought of food
- leads to increased gastric secretions and motility

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16
Q

what is phase 2 of gastric secretion?

A

gastric phase
- initiated by distension of stomach stretch receptors and chemoreceptors detecting increased pH due to food
- leads to secretion of gastrin and gastric juices
- promotes peristalsis

17
Q

what is phase 3 of gastric secretion?

A

intestinal phase
- initiated by chyme entering duodenum
- leads to release of hormones (GIP, secretin, CCK) which inhibits gastric secretion and emptying
- prevents overload of duodenum

18
Q

what is gastric emptying?

A

process regulated by neural reflexes and hormones to control movement of food from stomach to intestine

19
Q

what is the neural reflex involved in gastric emptying?

A

enterogastric reflex - inhibits parasympathetic stimulation and simulating sympathetic impulses to regulate gastric emptying.

20
Q

what stimulates gastric emptying?

A

nerve impulses in response to distension of stomach and release of gastric gastrin - promotes food movement into intestine

21
Q

what inhibits gastric emptying?

A

factors like distension of duodenum and presence of acidic chyme, triggering enterogastric reflex and release of GIP and CCK - inhibits gastric emptying

22
Q

how do parasympathetic impulses affect digestion?

A
  • they increase motility of small intestine
  • stimulate secretion of pancreatic enzymes
  • increase bile production
23
Q

how do sympathetic impulses affect digestion?

A

decreases intestinal motility