The Digestive System - Chapter 24 Flashcards

1
Q

The enzymatic breakdown of large molecules into their basic building blocks is called:

A

chemical digestion

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2
Q

The outer layer of the digestive tract is known as the:

A

serosa

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3
Q

Double sheets of peritoneum that provide support and stability for the organs of the peritoneal cavity are the:

A

mesenteries

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4
Q

A branch of the hepatic portal vein, hepatic artery proper, and branch of the bile duct form the:

A

a portal area

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5
Q

Most of the digestive tract is lined by _______ epithelium.

A

simple columnar

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6
Q

Regional movements that occur in the small intestine and function to churn and fragment the digestive material are called:

A

segmentation

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7
Q

Bile release from the gallbladder into the duodenim occurs only under the stimulation of:

A

cholecystokinin

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8
Q

The major functions of the large intestine are:

A

reabsorption of water and compaction of feces, absorption of vitamins liberated by bacterial action, and storage of fecal material prior to defecation.

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9
Q

vitamins generated by bacteria in the colon are

A

Vitamin K, Biotin, and Pantothenic Acid

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10
Q

The final enzymatic steps in the digestive process are accomplished by:

A

brush border enzymes of the intestinal microvilli

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11
Q

What are the six main functions of the digestive system?

A
  1. Ingestion
  2. Mechanical Processing
  3. Secretion
  4. Digestion (conversion into a form digestible by cells)
  5. Absorption
  6. Excretion
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12
Q

Name and describe the layers of the digestive tract, proceeding from the innermost layer nearest the lumen to the outermost layer.

A
  1. Mucosa (innermost)
  2. Submucosa
  3. Muscularis
  4. Serosa
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13
Q

What three basic mechanisms regulate the activities of the digestive tract?

A

Local, Hormonal, and Neural Mechanisms

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14
Q

What are the three phases of swallowing and how are they controlled?

A
  1. Buccal
  2. Pharyngeal
  3. Esophageal
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15
Q

What are the primary digestive functions of the pancreas?

A

provides digestive enzymes and bicarbonate ions that elevate the pH of the chyme.

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16
Q

Which hormones produced by duodenal enteroendocrine cells effectively coordinate digestive functions?

A

Enterocrinin, Secretin, Cholecystokinin, Gastric Inhibitory Peptide (GIP), Vasoactive Intestinal Peptide (VIP), Gastrin, Motilin, Villikinin, somatostatin

17
Q

What are the three primary functions of the large intestine?

A

reabsorbs water and compacts the intestinal contents into feces, absorbs important vitamins liberated by bacterial action, and stores fecal material prior to defecation.

18
Q

What two positive feedback loops are involved in the defecation reflex?

A
  1. Stretch receptors in the rectal walls, which promote a series of peristaltic contractions in the colon and rectum, moving feces toward the anus
  2. The sacral parasympathetic system, also activated by the stretch receptors, which stimulates peristalisis by motor commands distributed by the pelvic nerves.
19
Q
  1. During defecation,
A

stretch receptors in the rectal wall initiate a series of peristaltic contractions in the colon and rectum and stretch receptors in the rectal wall activate parasympathetic centers in the sacral region of the spinal cord.

20
Q

Increased parasympathetic stimulation of the intestine would NOT result in:

A

decreased motility, decrease secretion, decreased sensitivity of local reflexes, decreased segmentation.

21
Q

A drop in pH below 4.5 in the duodenum stimulates the secretion of

A

secretin

22
Q

Through which layers of a molar would an oral surgeon drill to perform a root canal?

A

drilling through the ENAMEL and DENTIN

23
Q

How is the epithelium of the stomach protected from digestion?

A

mucous secretions of it’s epithelial lining and by neural and hormonal control over the times and rates of acid secretion.

24
Q

How does each of the three phases of gastric secretion promote and facilitate gastric control?

A
  1. Cephalic Phase - Begins with the sight or thought of food. Directed by the CNS, this phase prepares the stomach to receive food.
  2. Gastric Phase - Begins with the arrival of food in the stomach, initiated by distension of the stomach, an increase in the pH of the gastric contents, and the presence of undigested materials in the stomach.
  3. Intestinal Phase - Begins when chyme starts to enter the small intestine. Controls the rate of gastric emptying and ensures that the secretory digestive, and absorptive functions of the small intestine can proceeded reasonable efficiently.
25
Q

Nutritionists have found that after a heavy meal, the pH of blood increases slightly, especially in the veins that carry blood away from the stomach. What causes this increase in blood pH?

A

After a heavy meal, bicarbonate ions pass from the parietal cells of the stomach into the interstitial fluid. The diffusion of bicarbonate ions from the interstitial fluid into the bloodstream increases blood pH. This sudden influx of bicarbonate ions into the bloodstream has been called the alkaline tide.

26
Q

Some people with gallstones develop pancreatitis. How could this occur?

A

If the gallstone is small enough, it can pass through the common bile duct and block the pancreatic duct. Enzymes from the pancreas then cannot reach the small intestine. As the enzymes accumulate they irritate the duct and ultimately the exocrine pancreas producing pancreatitis.

27
Q

Harry is suffering from an obstruction of his colon. He notices that when he urinates, the color of his urine is much darker than normal and he wonders if there is any relationship between the color of his urine and his intestinal obstruction. What would you tell him?

A

Likely due to the increase amounts of pigment UROBILIN, which gives urine it’s normal yellow color. Urobilin is derived from urobilinogen, which is formed in the large intestine by the action of intestinal bacteria on bile pigments. In an intestinal obstruction, the bile pigments cannot be eliminated by their normal route, so a larger-than-normal amount diffuses into the bloodstream, where the kidneys eliminate it.

28
Q

A condition known as lactose intolerance is characterized by painful abdominal cramping, gas, and diarrhea. The cause of the problem is an inability to digest the mil sugar lactose. How would this cause the observed signs and symptoms?

A

If an individual cannot digest lactose, this sugar passes into the large intestine in an undigested form. The presences of extra sugar in the chyme increases its osmolarity, so less water is reabsorbed by the intestinal mucosa. The bacteria that inhabit the large intestin can metabolize the lactose, and in the process they can produce large amounts of carbon dioxide. This gas overstretches the intestine, which stimulates local reflexes that increase peristalisis. The combination of the more-fluid contents and increased peristalsis causes diarrhea. The over-expansion of the intestine by gas, which is directly related to increased gas production by the bacteria, causes severe pain and abdominal cramping.

29
Q

Recently, more people have turned to surgery to help them lose weight. One form of weight control surgery involves stapling a portion of the stomach shut, creating a smaller volume. How would such a surgery result in weight loss?

A

Reduction of the volume of food (an thus calories) consumed because the person feels full after eating a small amount.

30
Q

What is the function of Vasoactive intestinal Peptide?

A

VIP stimulates the secretion of intestinal glands, dilates regional capillaries, and inhibits acid producation in the stomach.

31
Q

What is the function of Gastrin?

A

secreted by G cells in the duodenum when they are exposed to large quantities of incompletely digested proteins

32
Q

What is the function of Motilin?

A

stimulates intestinal contractions

33
Q

What is the function of Villikinin?

A

Promotes the movement of villi and associated lymph flow

34
Q

What is the function of Somtostatin?

A

inhibits gastric secretion