The Cell Cycle And Mitosis Flashcards
What is the cell cycle
The regulated sequence of events that occurs between one cell division and the next
What are the three phases of the cell cycle
-interphase
-nuclear division(mitosis)
-cell division(cytokinesis)
What is the length of the cell cycle dependent on
Dependent on environmental conditions, the cell type and the organism
What are cyclins
The chemical signals that trigger the movement from one cell cycle phase to another
What are the three phases of interphase
-Gap 1(G1)
-synthesis
-gap 2 (G2)
What happens during gap 1 in interphase
Cell makes more organelles and proteins ready for cell division
What happens during synthesis phase of interphase
DNA replicates, the chromosome becomes two sister(identical) chromatids joined together by a centromere
What happens during gap 2 phase of interphase
-cell keeps growing
-new DNA that has been synthesised is checked and any errors are usually repaired
-other preparations for cell division are made eg production of tubulin protein which is used to make microtubules for the mitotic spindle
What are sister chromatids
Identical chromatids joined together in the same chromosome by a centromere
What are the four phases of mitosis phase and how to remember stages
Prophase where the cell Prepares to divide
Metaphase where the chromosomes align along the Middle
Anaphase where the chromosomes move Away from each other
Telophase where Two nuclei reform
What happens during prophase
-chromosomes condense and are now visible when stained
-the chromosomes consist of two identical sister chromatids joined together at the centromere with each containing one DNA molecule
-the two centrosomes(replicated in G2) move towards opposite poles
-spindle fibres(protein microtubules) begin to extend from the centrosomes(which consist of two centrioles in animal cells)
-nuclear envelope breaks down into small vesicles
What happens during metaphase
-centrosomes reach opposite poles
-spindle fibres continue to extend from centrosomes
-chromosomes line up at the equator of the spindle so are equidistant to the two centrosome poles
-spindle fibres reach the chromosomes and attach to the centromeres
-each sister chromatid is attached to a spindle fibre originating from opposite poles
What are spindle fibres
Protein microtubules that divide the sister chromatids and extend from centrosomes
What happens during anaphase
-sister chromatids separate at the centromere and the centromere divides in two
-spindle fibres begin to shorten
-the separated sister chromatids (now called chromosomes) are pulled to opposite poles by spindle fibres and are pulled centromere first towards the centrosomes
What happens in telophase
-chromosomes arrive at opposite poles and begin to de-condense
-nuclear envelopes begin to reform around each set of chromosomes
-spindle fibres break down