The beeties

Question 1

Thalassemia

Answer 1

any of a group of hereditary hemolytic diseases caused by faulty hemoglobin synthesis, widespread in Mediterranean, African, and Asian countries.

Question 2

Prandial

Answer 2

During or related to dinner or lunch

Question 3

Pramlintide

Answer 3

A synthetic form of the B-cell produced hormone amylin, which aids in suppressing glucagon secretion

Question 4

Type I tx other than slin

Answer 4

Prandial injections of pramlintide, B-cell transplantation or combined kidney/pancreas transplantation

Question 5

How long can you keep room temp slin

Answer 5

30 days

Question 6

Standard dose of insulin

Answer 6

100units/mL (U100). Can come in 500units/ml (U500)

Question 7

Typically dosing regimen of insulin

Answer 7

Basal insulin - once daily long acting or twice daily intermediate acting and prandial dose 5-30 minutes before meal of 1 iu per 15g carbs

Question 8

Rate of insulin pumps typically

Answer 8

0.5 to 1.5/units/hour

Question 9

Amylin

Answer 9

Synthetic form is pramlintide, on top of suppressing glucagon it also reduces hemoglobin A1C, slows gastic emptying, and promotes satiety.

Question 10

Transplants

Answer 10

Pancreas, pancreas/kidney, and pancreas after kidney. Long term use of sirolumus and tacrolimus is required

Question 11

Edmonton protocol

Answer 11

Islet cell transplantation. Insulin independence but 2 years after 76% need exogenous insulin again