The antibiotic man Flashcards

1
Q

What antibiotic can be used as an alternative to gentamicin?

A

Aztreonam

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2
Q

What stain of bacteria is gentamicin active against

A

Gram negative

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3
Q

What stain of bacteria is vancomycin active against?

A

Gram positive

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4
Q

What antibiotic is very good for covering anaerobes?

A

Metronidazole

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5
Q

If NEWS is > 5 what should you consider?

A

SEPSIS

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6
Q

How long do you have to complete the sepsis 6 bundle?

A

1 HOUR

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7
Q

What is the treatment for epiglottitis/supraglottitis?

A

Ceftriaxone

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8
Q

What is the treatment for mild/mod community acquired pneumonia?

A

Amoxicillin (IV/PO) 5 days

If penicillin allergic:
Doxycycline

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9
Q

What is the treatment for severe community acquired pneumonia?

A

Co-amoxiclav IV + Doxycycline PO

If penicillin allergic - Levofloxacin IV

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10
Q

If a patient is in ICU or HDU with community acquired pneumonia, what antibiotics should they be given?

A

Co-amoxiclav IV
Clarithromycin IV

If penicillin allergic:
Levofloxacin IV

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11
Q

What is the step down for severe community acquired pneumonia when the patient is transferred from IV treatment to oral treatment?

A

Doxycycline

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12
Q

What is the treatment for a severe hospital acquired pneumonia?

A

IV amoxicillin and gentamicin

If penicillin allergic:
IV Co-trimoxazole + gentamicin

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13
Q

What is the step down from IV to oral therapy for a patient who had severe hospital acquired pneumonia?

A

Co-trimoxazole

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14
Q

What is the treatment for a non-severe hospital acquired pneumonia?

A

PO amoxicillin 5 days

If penicillin allergic: doxycycline

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15
Q

When should antibiotics be given in an exacerbation of COPD?

A

If high sputum purulence or consolidation on CXR or signs of pneumonia

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16
Q

What is the antibiotic treatment for an exacerbation of COPD?

A

Amoxicillin

If penicillin allergic: doxycycline

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17
Q

What is the treatment for native valve indolent endocarditis?

A

Amoxicillin IV +

Gentamicin IV

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18
Q

What is the treatment for native valve severe sepsis endocarditis?

A

Flucloxacillin IV

19
Q

What is the treatment for prosthetic valve endocarditis or suspected MRSA?

A

Vancomycin IV
Gentamicin IV

When therapeutic levels reached, add rifampicin PO

20
Q

What is the treatment for non severe C.diff?

A

Metronidazole PO

21
Q

What is the treatment for severe C.diff?

A

Vancomycin PO +/- IV metronidazole

22
Q

What is the treatment for peritonitis/biliary tract/Intra-abdominal infections?

A

IV amoxicillin + metronidazole + gentamicin

If penicillin allergic: IV Vancomycin + metronidazole + gentamicin

Step down to PO co-trimoxazole and metronidazole

23
Q

What is the treatment for proven spontaneous bacterial peritonitis (severe)?

A

Pip-taz IV

Step down to co-trimoxazole

24
Q

What is the treatment for proven spontaneous bacterial peritonitis (mild)?

A

Co-trimoxazole PO

25
Q

Should you treat a UTI in a patient with a catheter and no clinical signs/symptoms of infection?

A

No

If definite infection, treat as complicated UTI

26
Q

What is the treatment for an uncomplicated female lower UTI?

A

Nitrofurantoin or trimethoprim

27
Q

What is the treatment for an uncatheterised male UTI?

A

Nitrofurantoin or trimethoprim

28
Q

Should you treat a UTI in older adults if they are asymptomatic?

A

No

29
Q

What is the treatment for a complicated UTI/Pylonephritis/Urosepsis?

A

IV amoxicilliln and gentamicin

If penicillin allergic: IV co-trimoxazole and gentamicin

Step down to PO co-trimoxazole or as per sensitivities

30
Q

What is the treatment for cellulitis?

A

Flucloxacillin IV/PO

If penicillin allergic: Doxycycline PO

31
Q

What is the treatment for a mild diabetic foot infection?

A

Fluclox or doxycycline

32
Q

What is the treatment for a moderate diabetic foot infection?

A

Fluclox + metronidazole

Or doxycycline + metronidazole

33
Q

What is the treatment for open fracture prophylaxis?

A

IV Cefuroxime

34
Q

What is the treatment for meningitis?

A

Ceftriaxone and dexamethasone started for 4 days or with antibiotics.

35
Q

What should you add to meningitis treatment if you suspect encephalitis?

A

Aciclovir

36
Q

What should you add to meningitis treatment if the patient is immunocompromised or over 60?

A

Amoxicillin

37
Q

What is the treatment for oral thrush?

A

Miconazole gel

38
Q

What is the treatment for non-severe hospital acquired pneumonia?

A

Amoxicillin

If penicillin allergic: doxycycline

39
Q

What is the treatment for non-severe aspiration pneumonia?

A

Amoxicillin and metronidazole

If penicillin allergic: doxycycline and metronidazole

40
Q

What is the treatment for severe aspiration pneumonia

A

IV amoxicillin, gentamicin and metronidazole

If penicillin allergic, replace amox with doxycycline or clarithromycin

41
Q

What is the step down to oral for severe aspiration pneumonia?

A

Amoxicillin and metronidazole

If penicillin allergic: doxycycline and metronidazole

42
Q

What is the treatment for an acute cough/bronchitis?

A

Give no significant benefit. Only give in frail elderly.

Amoxicillin or doxycycline if allergic

43
Q

What is the treatment for acute septic arthritis/osteomyelitis?

A

Flucloxacillin IV

44
Q

What is the treatment for a severe systemic infection of unknown source?

A

Amox, met and gent

Vanc, met and gent