General Sepsis Flashcards
Define colonisation
Presence of a microbe in the human body without an inflammatory response
Define infection
Inflammation due to a microbe
Define bacteraemia
Presence of viable bacteria in the blood
Define sepsis
Life-threatening organ dysfunction caused by a dysregulated host response to infection
Define septic shock
Subset of sepsis
Circulatory and cellular/metabolic dysfunciton associated with a higher risk of mortality
Patient has sepsis + you have tried to resuscitate but afte adequate attempts they are still not responding to treatment
Will septicaemia ever be the answer to any question?
NO
Define virulence
Likelihood of causing disease
Define opportunistic pathogen
Infectious microorganism that is normally commensal/does not harm host but can cause disease when host’s resistance is low e.g. immunosuppression
What is an accidental pathogen?
Pure random one
example - infection from a monkey
Like proper random
What are the local signs/symptoms of sepsis?
Pain
Tenderness
Guarding
Blood PR if appropriate
What are the systemic signs/symptoms of sepsis?
Fever Chills/rigors Nausea/vomiting Constipation/diarrhoea Malaise/anorexia
What causes peritonitis?
Leakage of bowel contents into sterile peritoneal cavity
Leaky blood vessels happen in sepsis. True or false?
True
What does a patient have to score on SIRS in order to be diagnosed with sepsis?
2 or more
How many points on qSOFA does a patient need for sepsis to be considered?
2 or more
