the ageing brain Flashcards

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1
Q

what is affected by the ageing brain

A

vascular changes, anatomical changes, cellular and neuronal changes, cognitive changes

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2
Q

what is the limbic system in control of

A

learning, memory and emotion

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3
Q

what re the frontal lobes in control of

A

planning, strategy, working memory

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4
Q

what re the substantial nigra in control of

A

movement, reward and learning

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5
Q

what is the cerebellum in control of

A

movement, balance, emotion

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6
Q

what is the caudate in control of

A

executive functions, reward system

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7
Q

what is fluid intelligence

A

logical problem solving

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8
Q

is fluid intelligence affected by ageing

A

yes

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9
Q

what are some of the brain functions (memory) that decrease due to normal ageing

A

very few changes to implicit, short-terms and procedural memory
gradual decline in episodic memory
recognition works more on familiarity rather than recollection
reduction in prospective memory

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10
Q

what brain functions aren’t affected by ageing

A

knowledge and wisdom continue to grow, the ability to apply knowledge to skills doesn’t get affected, vocabulary grows, recognition memory doesn’t change

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11
Q

what is the neuropsychological theory for the ageing brain

A

task performance depends on intactness of different parts of the brain, especially the hippocampus and PFC

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12
Q

what is the general resource theory of the ageing brain

A

decline in activity to do any task can be explained by a decline in a general ability such as processing speed on attention

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13
Q

how to improve cognitive function

A

physical activity, physical health, mental health, stress management, diet, social support

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14
Q

what’s the differences between normal ageing and pathological ageing

A

typical ageing = memory loss, slower to work things out, cant multi-task
pathological = getting lost in familiar places, forgetting a lot, tremors, difficulty in following stories

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15
Q

what are the symptoms of dementia

A

memory loss, difficulty with tasks and language, impaired judgement, personality change

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16
Q

what are the causes of dementia

A

neuronal degeneration, blood vessel injury, neurotoxic reactions to alcohol or drugs, infection in the nervous system

17
Q

what causes Parkinson

A

the degeneration of dopamine (producing nerve cells - dopaminergic cells)

18
Q

what does the neuronal deviation disrupt in parkinsons

A

the CNS capacity to control and coordinate muscle movements

19
Q

where in the brain is the site for neuronal degeneration in Parkinson’s

A

the substantial nigra

20
Q

in AD, how fast is the deterioration

A

slow

21
Q

how long does it take for someone to die form AD

A

4-8 years

22
Q

what are the symptoms of AD

A

speech becomes monosyllabic and disappears, behavioural and emotional disturbance , loss of bladder control and bowel, mobility decreases

23
Q

how many people in 2001 had dementia

A

24 million

24
Q

how many people in 2040 will have dementia

A

84 million

25
Q

why is there an increase in dementia cases

A

people are living longer

26
Q

what percentage does dementia effect people 60-64

A

1%

27
Q

what percentage does dementia effect people 85 +

A

24% and 35%

28
Q

what are the causes of AD

A

age, genetics, depression, head injury, obesity, smoking

29
Q

Brain based markers for AD

A

brain shrinkage, ventricular enlargement, presence of neurofibrillary tangles, amyloid plaque

30
Q

where in the brain is most affected by tangles and plaque in AD

A

temporal and frontal lobes

31
Q

what are neurofibrillary tangles

A

they’re intraneuronal structures composed of protein

32
Q

what is amyloid plaque and AD

A

cholingeric pathways of AD patients are damaged by build up of amyloid plaques

33
Q

what is the treatment for AD

A

there is no cure, drug therapy delays