THC/Meth

Question 1

Compounds that give negative results for THC and Meth

Answer 1

1. Glucose
2. Niacinamide
3. Aspartame
4. Histamine
5. Morphine
6. Caffeine

(concentration up to 100 μg/mL)

Question 2

Principle Tetrahydrocannabinol (THC) and Methamphetamine (Meth)

Answer 2

— a device composed of 2-6 chromatographic strips treated with antibody colloidal gold conjugate and membrane treated with drug conjugate and control reagent.

If sufficient drug is present in the urine, it binds with the conjugate, preventing it from binding to the drug conjugate immobilizing the test region

Any unbound conjugate will migrate up the strip to the control region where it binds to the control reagent producing a pink/purple band.

Question 3

Give the results for Negative, Positive, and Invalid

Answer 3

✅ A Negative specimen produces 2️⃣ distinct color lines, BOTH test/control area

✅ A positive specimen produces only 1️⃣ color line in the control region.

✅ Invalid : No distinct color bands in both test and control region

Question 4

THC (Tetra-hydro-cannabinol) and Meth induces?

Answer 4

MJ🍃🚬
Altered mood and sensory perceptions
Increased heart rate
Impaired short term memory
Anxiety
Paranoia
Depression
Confusion

Methamphetamine 💊💉
Euphoria
Stimulates the central nervous system
Alertness
Increased energy and power

Question 5

Cannabinoids therapy for:

Answer 5

Glaucoma
Parsea (due to chemotherapy)

Question 6

THC Withdrawal causes:

Answer 6

Restlessness
Insomnia
Anorexia
Nausea

Question 7

Major THC urinary metabolite

Answer 7

11-nor-delta-9-tetrahydrocannabinol-9-
carboxylic acid (THC-COOH) and its glucuronide ……… in 50 ng/ml urine

Question 8

Limitations of the test (BOTH)

Answer 8

✅ Adulterants , such as bleach or strong oxidizing agents , when added to urine specimens may produce erroneous test results regardless of the of analysis method used.

✅ The test is a qualitative screening assay and not suggested for determining the quantitative level of DOA in urine.

✅ The product is designed to be used for detection of DOA and or metabolites in human urine only

Question 9

STEPS

Answer 9

✅ Bring-Remove-Remove
✅ Immerse-Hold-Withdraw
✅ Read…..(between 3-8 minutes)

1. Bring all materials and specimens to room temperature.
2. Remove the test device from the sealed foil pouch.
3. Remove the cap from the device.
4. Immerse the bottom end of the test strips (the sample pads) into a urine sample with the arrows pointing toward the specimen. (keep the level of the urine sample below the bottom of the plastic card or the maximum line marked on the strips.)
5. Hold the device in the urine until a reddish color appears at the lower edge of the test membrane (approximately 10 seconds).

6.Withdraw the device from the urine sample, and replace the cover.

7.Read results between 3- 8 minutes.

Question 10

Screening cutoff for THC and Meth in urine

Answer 10

THC – 50 nanograms per milliliter
Meth – 500 nanograms per milliliter