Textbook Questions Flashcards
Thiazide Diuretics
the initial drug treatment for hypertension in patients without compelling indications for alternative drug treatment
Is it appropriate to combine two thiazide or two beta-blocking drugs to successfully treat hypertension
no. It’s ok to combine things that lower BP by different mechanisms, but not many of the same
Which class of anti-HTN meds work best for black patients?
Diuretics.
What comorbid conditions require careful use/avoidance of anti-HTN drugs?
hyper/pokalemia, diabetes, depression, renal insufficiency, dyslipidemia, gout, collagen diseases, liver disease, AV heart block, heart failure, preeclampsia
Algorithm for treating HTN
- diet/lifestyle changes
- diuretics
- beta antagonists
- alpha antagonists
- Alpha2 agonists
- Vasodilators
- Ace inhibitors
General principles for use of anti-dysrrhythmic drugs
They are dangerous because they change the electric/contractile activity of the heart.
Contraindications for antiplatelet/thrombolytic drugs
bleeding, internal bleeding. assess mental status. BP, heart rate, mucous membranes, HTN, ischemic stroke history
Vytorin
ezetimibe and simvastatin
simvastatin is a an HMG-CoA reductase inhibitor.
ezetimibe is a selective inhibitor of intestinal cholesterol