Tetracylines Flashcards
1
Q
Mechanism of action
A
Protein synthesis inhibitor
2
Q
Therapeutic uses
A
Rocky mountain spotted fever, typhus, cholera, Lymes, peptic ulcers, chlamydia.
Newer ones for MRSA
3
Q
Side effects
A
Teeth yellowing in children under 8, super infections
Nausea vomiting diarrhea
Photosensitity
Drug resistance
Rash
Anaphylaxis
4
Q
Contraindications
A
Not for Pregnancy (cat D)
Not for children under 8
Sever hepatic or renal disease
5
Q
Drug interactions
A
Milk, iron
Decreases oral contraceptive efficacy
Acitretin
Lomitapide
Not with penicillins or cephalasporins
6
Q
Suffix
A
Ends in cycline
7
Q
Prototype drug
A
Tetracycline
8
Q
Considerations
A
Increase fluid to 3 L. Avoid sun