Tetracylines Flashcards

1
Q

Mechanism of action

A

Protein synthesis inhibitor

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2
Q

Therapeutic uses

A

Rocky mountain spotted fever, typhus, cholera, Lymes, peptic ulcers, chlamydia.
Newer ones for MRSA

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3
Q

Side effects

A

Teeth yellowing in children under 8, super infections
Nausea vomiting diarrhea
Photosensitity
Drug resistance
Rash
Anaphylaxis

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4
Q

Contraindications

A

Not for Pregnancy (cat D)
Not for children under 8
Sever hepatic or renal disease

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5
Q

Drug interactions

A

Milk, iron
Decreases oral contraceptive efficacy
Acitretin
Lomitapide
Not with penicillins or cephalasporins

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6
Q

Suffix

A

Ends in cycline

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7
Q

Prototype drug

A

Tetracycline

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8
Q

Considerations

A

Increase fluid to 3 L. Avoid sun

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