Antifungal Flashcards
1
Q
Mechanism of action
A
Bind to sterols and makes Cell wall leaky
2
Q
Therapeutic uses
A
Fungal infections
3
Q
Side effects
A
Superficial: minimal side effects, minor skin irritation, nausea vomiting diarrhea
Systemic: headache, hypokalemia, rash fever, chills, nausea, hypo magnesium, nephrotoxic
4
Q
Drug interactions
A
Decreases oral contraceptive efficacy
Increased bleeding risk if taking with anticoagulants
5
Q
Suffix
A
Some end in azole
6
Q
Prototype drug
A
Amphotercin (systemic)
Nysatin (superficial)
Fluconazole
7
Q
Considerations
A
Refrigerate and shake the drug
