Antitubecular Drugs Flashcards

1
Q

Mechanism of action

A

Isoniazid: Cell wall synthesis inhibbitors
Rifampin: decreases pH

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2
Q

Therapeutic uses

A

Treat TB

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3
Q

Side effects

A

Isoniazid: anaphylaxis, hepatotoxicity, peripheral neuropathy, optic nueritis
Rifampin: orange bodily fluids

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4
Q

Drug interactions

A

Decrease oral contraceptive efficacy
Avoid Alchohol, tyramine

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5
Q

Considerations

A

Latent TB infection: 6- 12 months of drugs
Active TB infection: 2 years of drugs
Increase b6 foods (eg. Rice, pistachios)
High resistance likelihood

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