Antitubecular Drugs Flashcards
1
Q
Mechanism of action
A
Isoniazid: Cell wall synthesis inhibbitors
Rifampin: decreases pH
2
Q
Therapeutic uses
A
Treat TB
3
Q
Side effects
A
Isoniazid: anaphylaxis, hepatotoxicity, peripheral neuropathy, optic nueritis
Rifampin: orange bodily fluids
4
Q
Drug interactions
A
Decrease oral contraceptive efficacy
Avoid Alchohol, tyramine
5
Q
Considerations
A
Latent TB infection: 6- 12 months of drugs
Active TB infection: 2 years of drugs
Increase b6 foods (eg. Rice, pistachios)
High resistance likelihood