Tetracyclines Flashcards
Are Tetracyclines bacteriostatic or cidal?
Bacteriostatic
Name a few Tetracyclines
Tetracycline
Doxycycline
Tigecycline
MOA for Tetracyclines
Binds 30s ribosomal subunit
Protein synthesis
Uses for Tetracycline?
Broad spectrum
URI
LRI
SSTI
Does food or milk decrease or increase absorption?
Decrease
ADE for Teracycline
Photosensitivity
Tooth discoloration
NVD
Candidal infection
Doxy frist line for
RMSF
Lyme
Vibrio
Acne
Tetracycline preggo cat
D
Is it safe to take expired (outdated) tetracycline?
Serious renal issues if you take expired tetracycline
Dairy and Doxy?
NO! DONT DO IT
ADRs with doxy?
Usual to include elevated LFTs, Blacktounge and Jarish-Hermheir reaction (Rare)
Doxy preggo and interations
Cat D
Interacts with anticoags
Digoxin
Calcium (tums/dairy)
MInocycline same as doxy all aorund but….
Good CSF penetration
can cause vertigo
Skin discoloration (grey color)