tetracycline, sulfonamide, quinolines

Question 1

The hydroxyl/ Ketone groups on tetracycline will have no activity if taken with foods containing what compounds?

Answer 1

Calcium/ Magnesium

Question 2

Tetracycline is a good alternative to what type of antibiotic?

Answer 2

Macrolide

Question 3

Tetracycline spectrum?

Answer 3

Broad

Question 4

Tetracycline MOA

Answer 4

30s ribosome

Question 5

Tetracycline static or cidal?

Answer 5

Static

Question 6

Tetracycline inhibits what?

Answer 6

Bone growth, but it is reversible

Question 7

Tetracycline side effects

Answer 7

Nausea in 90%

Hepatotoxic, especially in pregnant woman

Question 8

Tetracycline is treatment for what?

Answer 8

Cholera

Acne

Question 9

Sulfonamides competes with?

Answer 9

PABA

Question 10

Bacteria need to build their own folic acid. T or F?

Answer 10

True

Question 11

If Trimethoprim is used with a sulfonamide will it have a static or cidal effect?

Answer 11

Cidal if using both

Static if using one

Question 12

Sulfonamide spectrum?

Answer 12

Broad

Question 13

Where is sulfonamide metabolized/excreted?

side effects?

Answer 13

M: Liver
E: Urine
Stevens Johnson Syndrome

Question 14

Trimethoprim Inhibits which step of folic acid synthesis?

Answer 14

2nd step

Question 15

Trimethoprim is used to treat?

Answer 15

Malaria

Question 16

Quinolone

Answer 16

Broad spectrum
Bactericidal
Used for tuberculosis

Question 17

Quinolone MOA

Answer 17

Inhibit folding of 2 DNA strands

Question 18

Quinolone is a good alternative for what 2 drugs?

Answer 18

Amino-glycosides

Penicillin

Question 19

Quinolone should not be used when?

Answer 19

Pregnancy/ lactation/ periods of growth