testicular tumors Flashcards
age 30
gross- bulky mass lobulated cut surface, devoid of haemorrhage or necrosis and tunica albuginea is intact
seminoma
glycogen rich clear cytoplasm
demarcated lobules by delicate septa of fibrous tissue
syncytiotrophoblasts
coagulative necrosis without hemorrhage
seminoma
older men >65
non ITGCN
gross- mucoid cyst
micro- medium sized, numerous cells having round nucleus, scant eosinophilic cytoplasm.
smaller cells resembling spermatocyte
scattered giant cells
spermatocytic tumor
20-30 years
gross- ill-defined invasive mass
foci of hemorrage or necrosis
extension through the tunica albuginea
embroyonal carcinoma
micro:
primitive appearing cells in aveolar or tubular patterns
increased AFP and hCG
embroyonal carcinoma
childern up to 3 years
gross- uncapsulated
yellow white, mucinous appearance
micro- lacelike
schiller-Duval bodies (glomeruli like)
raised AFP
yolk sac
gross- small palpable noduels
hemorrhage and necrosis
micro- cytotrophoblastic with syncytiotrophoblastic cells
high HCG
may cause hyperthyrodim/gynaecomastia
spreads to LUNGS
choriocarcinoma
differentiate along multiple somatic cell lineages
gross- soild cartilaginous and cystic areas
mico- fibrous or myxoid stroma
teratoma
gross- nodule with a golden brown, homegenous cut surface
micro– crystalloid of reinke
testicular swelling
Gynecomastia
sexual precocity
leydid cell tumors
gross- bulge from surface
- yello-pink, cystic spaces
micro- lined by 2 layers inner tall columnar and outer cuboidal or flattened basal epithelium
- dense fibromuscular stroma
-corpora amylacea
BPH
