Testes, Penis, Scrotum Pathology Flashcards
vasitis nodosa
usually observed after vasectomy in the blind end of the transected vas deferens
resembles invasive adenocarcinoma, but the presence of sperm, chronic inflammation, and lack of atypia
Sertoli cell tumor
sex-cord stromal tumor
account for
characterized by closely packed cords or cells
can produce estrogen which can result in gynecomastia or impotence
Bowenoid papulosis
SCC in-situ multiple pigmented reddish brown papules on the external gentialia
association with HPV type 16
does NOT develop into invasive SCC
embyonal carcinoma
non-seminomatous tumor
2nd most common of the germ cell tumors
cells are large, with vesicular nuclei, prominent nucleoli, glandular structures
accumulation of fluid around the testis, due to fluid secreted into a potential space called the tunica vaginalis.
The TV is derived from extension of peritoneum wrapped around the testis
Most common cause of scrotal enlargement
Common problem among bikers
hydrocele
most common tumor seen in the testis over age 60 it is mostly from B-cells
testicular lymphoma
benign tumor probably mesothelial in origin
adenomatous tumor of the epididymis
Invasive SCC of penis
Most common cancer of the penis (95%) most cases occur in the uncircumcised males risk factors include poor hygiene, smoking, HPV infection (types 16 and 18) corpus spongiosum/cavernosum invasion important for staging
usually observed after vasectomy in the blind end of the transected vas deferens
resembles invasive adenocarcinoma, but the presence of sperm, chronic inflammation, and lack of atypia
vasitis nodosa
hydrocele
accumulation of fluid around the testis, due to fluid secreted into a potential space called the tunica vaginalis.
The TV is derived from extension of peritoneum wrapped around the testis
Most common cause of scrotal enlargement
Common problem among bikers
Peyronie’s disease
painful contractures of the penis may cause infertility
teratoma
non-seminomatous tumor
mature form is composed of somatic-type tissues that can include intestine-type glands, respiratory epithelium, cartilage, muscle, squamous epithelium
immature form have a worse outcome. they contain immature neuroepithelium, blastema, carcinoid, or cellular stroma
non-seminomatous tumor
2nd most common of the germ cell tumors
cells are large, with vesicular nuclei, prominent nucleoli, glandular structures
embyonal carcinoma
adenomatous tumor of the epididymis
benign tumor probably mesothelial in origin
seminomas
account for 40% of germ cell tumors
characterized by neoplastic germ cells in solid nests surrounded by fibrous septa, with a lymphocytic infiltrate
Most common cancer of the penis (95%)
most cases occur in the uncircumcised males
risk factors include poor hygiene, smoking, HPV infection (types 16 and 18)
corpus spongiosum/cavernosum invasion important for staging
Invasive SCC of penis
painful contractures of the penis may cause infertility
Peyronie’s disease
orifice of the prepuce is too small to retract over the head of the penis due to prepuce scarring from prior infection
phimosis
characterized by papillary excrescences present within tunica vaginalis which forms hydrocele sac papillae lined by bland cells with large nuclei and nucleoli
benign papillary mesothelioma
SCC in-situ multiple pigmented reddish brown papules on the external gentialia association with HPV type 16 does NOT develop into invasive SCC
Bowenoid papulosis
balanitis
inflammation/infection of the glans
sex-cord stromal tumor
account for
characterized by closely packed cords or cells
can produce estrogen which can result in gynecomastia or impotence
Sertoli cell tumor
non-seminomatous tumor
most common germ cell tumor in infants
characterized by microcystic pattern with Schiller-Duvall bodies
yolk sac tumor
varicocele
an abnormal enlargement of the vein that is in the scrotum draining the testicles
most common cause of left-sided scrotal enlargement in adult
bag of worms appearance
blockage of left renal vein
common cause of infertility
