Testes, Penis, Scrotum Pathology Flashcards

1
Q

vasitis nodosa

A

usually observed after vasectomy in the blind end of the transected vas deferens

resembles invasive adenocarcinoma, but the presence of sperm, chronic inflammation, and lack of atypia

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1
Q

Sertoli cell tumor

A

sex-cord stromal tumor

account for

characterized by closely packed cords or cells

can produce estrogen which can result in gynecomastia or impotence

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2
Q

Bowenoid papulosis

A

SCC in-situ multiple pigmented reddish brown papules on the external gentialia

association with HPV type 16

does NOT develop into invasive SCC

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2
Q

embyonal carcinoma

A

non-seminomatous tumor

2nd most common of the germ cell tumors

cells are large, with vesicular nuclei, prominent nucleoli, glandular structures

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2
Q

accumulation of fluid around the testis, due to fluid secreted into a potential space called the tunica vaginalis.

The TV is derived from extension of peritoneum wrapped around the testis

Most common cause of scrotal enlargement

Common problem among bikers

A

hydrocele

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2
Q

most common tumor seen in the testis over age 60 it is mostly from B-cells

A

testicular lymphoma

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3
Q

benign tumor probably mesothelial in origin

A

adenomatous tumor of the epididymis

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4
Q

Invasive SCC of penis

A

Most common cancer of the penis (95%) most cases occur in the uncircumcised males risk factors include poor hygiene, smoking, HPV infection (types 16 and 18) corpus spongiosum/cavernosum invasion important for staging

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5
Q

usually observed after vasectomy in the blind end of the transected vas deferens

resembles invasive adenocarcinoma, but the presence of sperm, chronic inflammation, and lack of atypia

A

vasitis nodosa

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6
Q

hydrocele

A

accumulation of fluid around the testis, due to fluid secreted into a potential space called the tunica vaginalis.

The TV is derived from extension of peritoneum wrapped around the testis

Most common cause of scrotal enlargement

Common problem among bikers

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7
Q

Peyronie’s disease

A

painful contractures of the penis may cause infertility

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8
Q

teratoma

A

non-seminomatous tumor

mature form is composed of somatic-type tissues that can include intestine-type glands, respiratory epithelium, cartilage, muscle, squamous epithelium

immature form have a worse outcome. they contain immature neuroepithelium, blastema, carcinoid, or cellular stroma

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9
Q

non-seminomatous tumor

2nd most common of the germ cell tumors

cells are large, with vesicular nuclei, prominent nucleoli, glandular structures

A

embyonal carcinoma

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10
Q

adenomatous tumor of the epididymis

A

benign tumor probably mesothelial in origin

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11
Q

seminomas

A

account for 40% of germ cell tumors

characterized by neoplastic germ cells in solid nests surrounded by fibrous septa, with a lymphocytic infiltrate

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12
Q

Most common cancer of the penis (95%)

most cases occur in the uncircumcised males

risk factors include poor hygiene, smoking, HPV infection (types 16 and 18)

corpus spongiosum/cavernosum invasion important for staging

A

Invasive SCC of penis

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13
Q

painful contractures of the penis may cause infertility

A

Peyronie’s disease

14
Q

orifice of the prepuce is too small to retract over the head of the penis due to prepuce scarring from prior infection

A

phimosis

15
Q

characterized by papillary excrescences present within tunica vaginalis which forms hydrocele sac papillae lined by bland cells with large nuclei and nucleoli

A

benign papillary mesothelioma

16
Q

SCC in-situ multiple pigmented reddish brown papules on the external gentialia association with HPV type 16 does NOT develop into invasive SCC

A

Bowenoid papulosis

17
Q

balanitis

A

inflammation/infection of the glans

19
Q

sex-cord stromal tumor

account for

characterized by closely packed cords or cells

can produce estrogen which can result in gynecomastia or impotence

A

Sertoli cell tumor

20
Q

non-seminomatous tumor

most common germ cell tumor in infants

characterized by microcystic pattern with Schiller-Duvall bodies

A

yolk sac tumor

22
Q

varicocele

A

an abnormal enlargement of the vein that is in the scrotum draining the testicles

most common cause of left-sided scrotal enlargement in adult

bag of worms appearance

blockage of left renal vein

common cause of infertility

24
Q

Bowen’s disease

A

SCC in-situ involves the shaft of the penis and scrotum

associated with HPV types 6 and 18

precursor for invasive squamous cell carcinoma (10%)

25
Q

Leydig cell tumors

A

sex-cord stromal tumors

account for 3-5% of all testicular tumors

characterized by clear cytoplasm, cells are not nested

25
Q

non-seminomatous tumor

mature form is composed of somatic-type tissues that can include intestine-type glands, respiratory epithelium, cartilage, muscle, squamous epithelium

immature form have a worse outcome. they contain immature neuroepithelium, blastema, carcinoid, or cellular stroma

A

teratoma

26
Q

yolk sac tumor

A

non-seminomatous tumor

most common germ cell tumor in infants characterized by microcystic pattern with Schiller-Duvall bodies

26
Q

choriocarcinoma

A

non-seminomatous tumor

they metastasize to the brain and lungs

characterized by multinucleated synctiotrophoblastic cells and mononuclear cytotrophoblast or intermediate trophoblast marker is bHCG

29
Q

balanoposthitis

A

inflammation/infection of the glans and prepuce

30
Q

testicular lymphoma

A

most common tumor seen in the testis over age 60

it is mostly from B-cells

31
Q

account for 40% of germ cell tumors

characterized by neoplastic germ cells in solid nests surrounded by fibrous septa, with a lymphocytic infiltrate

A

seminomas

33
Q

sex-cord stromal tumors

account for 3-5% of all testicular tumors

characterized by clear cytoplasm, cells are not nested

A

Leydig cell tumors

34
Q

erythroplasia of Queyrat

A

SCC in-situ redness located on the mucosal surface of the glans and prepuce

HPV type 16 association

precursor for invasive squamous cell carcinoma

35
Q

SCC in-situ involves the shaft of the penis and scrotum

associated with HPV types 6 and 18

precursor for invasive squamous cell carcinoma (10%)

A

Bowen’s disease

36
Q

an abnormal enlargement of the vein that is in the scrotum draining the testicles

most common cause of left-sided scrotal enlargement in adult

bag of worms appearance blockage of left renal vein common cause of infertility

A

varicocele

37
Q

inflammation/infection of the glans and prepuce

A

balanoposthitis

38
Q

phimosis

A

orifice of the prepuce is too small to retract over the head of the penis due to prepuce scarring from prior infection

39
Q

non-seminomatous tumor they metastasize to the brain and lungs characterized by multinucleated synctiotrophoblastic cells and mononuclear cytotrophoblast or intermediate trophoblast marker is bHCG

A

choriocarcinoma

40
Q

SCC in-situ

redness located on the mucosal surface of the glans and prepuce

HPV type 16 association

precursor for invasive squamous cell carcinoma

A

erythroplasia of Queyrat

41
Q

inflammation/infection of the glans

A

balanitis

42
Q

benign papillary mesothelioma

A

characterized by papillary excrescences

present within tunica vaginalis which forms hydrocele sac

papillae lined by bland cells with large nuclei and nucleoli