Male Drugs Flashcards

1
Q

finasteride

A

5-alpha reductase inhibitor used to treat benign prostate hyperplasia and male pattern baldness

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2
Q

stanozolol

A

17-alpha alkylated testosterone that is not easily metabolized by the liver and is given orally

hepatotoxic

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3
Q

testosterone

A

converted by armostase to estradiol by 5-alpha reducatase to DHT

activates androgen receptors

metabolized in the liver (high first pass effect)

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3
Q

GnRH analog, when given long-term causes gonadal suppression

used in conjunction with flutamide for treating metastatic prostate cancer

A

leuprolide

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4
Q

selective inhibitors of cGMP specific phosphodiesterase 5 (PDE5)

they enhance the effects of NO

used to treat erectile dysfunction

A

sildenafil / vardenafil / tadalafil

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5
Q

precursors of testosterone synthesis and may be used as nutritional supplementation, starts with A

A

androstenedione

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6
Q

DHT

A

responsible for male pattern balding, prostate hyperplasia plus other physiology

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7
Q

estradiol

A

induces fusion of the epiphysis plus other physiological responses

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7
Q

responsible for male pattern balding, prostate hyperplasia plus other physiology

A

DHT

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8
Q

induces fusion of the epiphysis plus other physiological responses

A

estradiol

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8
Q

prostaglandin E1 for intracavernous use to cause erection

A

alprostadil

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9
Q

17-alpha alkylated testosterone that is not easily metabolized by the liver and is given orally hepatotoxic

A

stanozolol

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10
Q

alprostadil

A

prostaglandin E1 for intracavernous use to cause erection

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12
Q

sildenafil / vardenafil / tadalafil

A

selective inhibitors of cGMP specific phosphodiesterase 5 (PDE5)

they enhance the effects of NO used to treat erectile dysfunction

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14
Q

androstenedione

A

precursors of testosterone synthesis and may be used as nutritional supplementation, starts with A

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16
Q

5-alpha reductase inhibitor used to treat benign prostate hyperplasia and male pattern baldness

A

finasteride

17
Q

flutamide

A

androgen receptor antagonist used with leuprolide for treating metastatic prostate cancer

18
Q

precursor of testosterone synthesis and may be used as nutritional supplementation, starts with D

A

DHEA

19
Q

leuprolide

A

GnRH analog, when given long-term causes gonadal suppression

used in conjunction with flutamide for treating metastatic prostate cancer

20
Q

androgen receptor antagonist used with leuprolide for treating metastatic prostate cancer

A

flutamide

21
Q

DHEA

A

precursor of testosterone synthesis and may be used as nutritional supplementation, starts with D

22
Q

converted by armostase to estradiol by 5-alpha reducatase to DHT activates androgen receptors metabolized in the liver (high first pass effect)

A

testosterone