Male Drugs Flashcards
(22 cards)
finasteride
5-alpha reductase inhibitor used to treat benign prostate hyperplasia and male pattern baldness
stanozolol
17-alpha alkylated testosterone that is not easily metabolized by the liver and is given orally
hepatotoxic
testosterone
converted by armostase to estradiol by 5-alpha reducatase to DHT
activates androgen receptors
metabolized in the liver (high first pass effect)
GnRH analog, when given long-term causes gonadal suppression
used in conjunction with flutamide for treating metastatic prostate cancer
leuprolide
selective inhibitors of cGMP specific phosphodiesterase 5 (PDE5)
they enhance the effects of NO
used to treat erectile dysfunction
sildenafil / vardenafil / tadalafil
precursors of testosterone synthesis and may be used as nutritional supplementation, starts with A
androstenedione
DHT
responsible for male pattern balding, prostate hyperplasia plus other physiology
estradiol
induces fusion of the epiphysis plus other physiological responses
responsible for male pattern balding, prostate hyperplasia plus other physiology
DHT
induces fusion of the epiphysis plus other physiological responses
estradiol
prostaglandin E1 for intracavernous use to cause erection
alprostadil
17-alpha alkylated testosterone that is not easily metabolized by the liver and is given orally hepatotoxic
stanozolol
alprostadil
prostaglandin E1 for intracavernous use to cause erection
sildenafil / vardenafil / tadalafil
selective inhibitors of cGMP specific phosphodiesterase 5 (PDE5)
they enhance the effects of NO used to treat erectile dysfunction
androstenedione
precursors of testosterone synthesis and may be used as nutritional supplementation, starts with A
5-alpha reductase inhibitor used to treat benign prostate hyperplasia and male pattern baldness
finasteride
flutamide
androgen receptor antagonist used with leuprolide for treating metastatic prostate cancer
precursor of testosterone synthesis and may be used as nutritional supplementation, starts with D
DHEA
leuprolide
GnRH analog, when given long-term causes gonadal suppression
used in conjunction with flutamide for treating metastatic prostate cancer
androgen receptor antagonist used with leuprolide for treating metastatic prostate cancer
flutamide
DHEA
precursor of testosterone synthesis and may be used as nutritional supplementation, starts with D
converted by armostase to estradiol by 5-alpha reducatase to DHT activates androgen receptors metabolized in the liver (high first pass effect)
testosterone
