Test Three: Intro To CNS Drugs Flashcards
What form of neuron communication do CNS drugs interfere with?
Analog encoding- chemical neurotransmission
What type of neuron signaling do local anesthetics block?
Digital encoding- reduces frequency of APs by blocking sodium channels
Neurotransmitter criteria
Synthesized in the pre-synaptic nerve
Stored in vesicles
released upon stimulation
rapid inactivation
Examples of biogenic amines
Epi, norepi, serotonin, histamine, dopamine, acetylcholine
Where in the CNS is Ach used?
Ventral/motor spinal cord, projections from cerebral cortex, limbic system, and thalamus
What are the types of receptors for acetylcholine?
Muscarinic, nicotinic, and neuromuscular junctions
Functions of Ach
mediates / modulates arousal , respiration,
motor activity, pain, vertigo, and memory
Drugs used to treat amid and odd disorders
anxiolytics, MAOI and tricyclic antidepressants