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1
Q

Zones of adrenal and production

A

Zona glomerusa (aldosterone) (exterior to the interior)
Zona fasciulara: cortisol
Zona reicularis: androgens
adrenal medulla: chromaffin

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2
Q

aldolase B deficcency (remove what from diet and enzyme?)

A

remove sucrose

Glucogeneisis is impaired

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3
Q

Enzyme deficient in essential fructosuria?

A

Frutikinase

benign condition

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4
Q

Hereditary fructose intolerance?

A

Hypoglycemia and vomiting after fructose
failure to thrive
Deficient in aldolase

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5
Q

Mycobacterium leprae?

A

Have patches with anesthesia on the skin
skin to skin contact
armadillo contac
depends on the strength of cell mediated antibody

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6
Q

borreliaburgdiferu?

A

Lyme disease (rash) with fever and malaise

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7
Q

Campylobacter fetus?

A

Gram - rod

mild enteritis in immunocompromised patiens

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8
Q

Cornybacterium diptheria

A

Gram + rod causing diptheria

upper respiratory infection complicated by polyneuritis and myocarditis

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9
Q

Treponema pallidoim?

A

Syphilis painless chancre over entire body

Tertiary syphilis results in skin and bone gummas and ascending aorta

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10
Q

Hemorroids (nerves)

A

pudendal nerve

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11
Q

splanic nerves?

A

Parasympathetic innrtvation to the pelvic and genital organs

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12
Q

Ilioinguinal nerve?

A

medial thigh, scrotum and penis of males

Mons pubis and labia majora in females

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13
Q

Changes in the adrenal gland?
ACTH
CONN
addison

A

Hyperplasia of glomerular layer: Conn (aldosterone)
Hyperplasia of adrenal medulla: pheo
Atophy of adrenal cortex; Addison

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14
Q

Types of blot procedure?

A

western blot: digest the protein and use antibody to bind to it

Northern blot: mRNA and seperated to bands. Probe with nucleotide

Southern blot: DNA sequences

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15
Q

Surgical options for parkinsons?

A

High frequency in the subthalamic nucleus

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16
Q

What is best treatement for bacteroides and why?

A
Gram negative anaerobe
ProduceB lactamase (so use inhibitors)

Clavulin, Pip Tazo, silbactam

17
Q

Cipro coverage

A

second generation quinolone
gram - rods including legionella and psuedomonas

(topimerase 2 inhibition)

18
Q

ceftriaxone

A

H influenzae
Klebseilla pneumonia
neisseria
Serratia

19
Q

Axithromycin

A

Chlamydia
Mycoplasma
H. Influenzae
Moraxella catarrhalis

20
Q

Vancomycin

A

tricyclic glycopeptide (gram positive bacteria)

21
Q

Side effects og grancyclovir and of spetra?

A

Neutropenia

22
Q

side effects of tuberculosis medications?

A

isonizaid: hepatitis
didanosine: pancreatitis

23
Q

side effects with foscarnet?

A

hypocalcemia
hypokalemia
hypomagisium
hypophopatemia

24
Q

Side effects of amiodarone?

A

hypothyroidism
hyperthyroidism
hypomagnsium
thyroiditis

25
Q

What is used to treat psoriasis?

A
Involves CD4 and CD8
Uses vitamin D analogs including:
calcipotriene
calcipotiol
calcitrual
tacalctrol

cyclosporine (inhibits nuclear transcription factor)
enthracept (inhibits TNF)

methrotrexate: folate metabolite binds to dihydrofolate
ustekinumab: monoclonanl antibody in psiariasis targets IL1 and IL2

26
Q

complication of crohn and UC?

A

Toxic megacolon

Due an x-ray to see it

27
Q

conditions associated with atopic dermatitis?

A

Allergic rhinitis
asthma
Atopic dermatitis

28
Q

what is glutean entreopathy?

A

dermatitis hepatiform

29
Q

How does isoniaziad work ?

A

acetylation

30
Q

Characteristics of Kartagner syndrome?

A

Dextrocardia
repeated infections
primarily a ciliary dyskinesia
will often have infertility

31
Q

What does C1 complement deficiency?

A

H influenzae
Strep pneumoniae
Neseeria mengingitis

32
Q

What happens with alveolar collapse?

A

surfactant in lamellar bodies