TEST FOR SECONDARY HEMOSTASIS

Question 1

Tests for secondary hemostasis:
CPA-STRDS

Answer 1

Clotting time
prothrombin time
activated partial thromboplastin time
stypven time
thrombin time
Reptilase time
Duckert’s Test
Substitution studies

Question 2

Measures Period Required for FREE FORMATION OF BLOOD TO CLOT after it has BEEN REMOVED FROM THE BODY

screen for problems in the blood clotting/coagulation mechanism

Answer 2

Clotting time

Question 3

2 methods of clotting time
2methods of capillary blood method

Answer 3

capilliary blood method
-slide drop
-dale and laidlaw’s method
lee and white method

Question 4

normal value for slide drop method

Answer 4

2-4 mins

Question 5

normal value for lee and white method

Answer 5

7-15 mins

Question 6

monitors the coagulation factors of the extrinsic and common pathway

used to monitor coumarin/coumadin/warfarin

Answer 6

Prothrombin time

Question 7

Normal Value for PT

Answer 7

10-13 seconds

Question 8

specimen for PT

Answer 8

PPP + thromboplastin + CaCl2

Question 9

standardized way of reporting PT (INR)

Answer 9

International Normalized Ratio

Question 10

Monitors the coagulation factors of Intrinsic and Common pathway

used to monitor heparin therapy

Answer 10

activated partial thromboplastin time

Question 11

normal value for aptt

Answer 11

<35 seconds

Question 12

specimen for aptt

Answer 12

PPP + appt reagent

Question 13

reagents for appt

Answer 13

Activator: (micronized silica, ellagic acid, cellite, kaolin)
phospholipid
CaCl2

Question 14

Used to detect deficiencies in fibrinogen
prothrombin
factor V and X

detects coagulation deficiencies in the common pathway

Answer 14

Stypven Time (russel viper venom time)

Question 15

normal value for Stypven time

Answer 15

6-10 seconds

Question 16

reagent for stypven time

Answer 16

east indian viper (Viperarusselli)

Question 17

detects fibrinogen deficiency
sensitive test in detecting heparin inhibition

Answer 17

Thrombin time

Question 18

thrombin time is prolonged in?
(FPPP)

Answer 18

Fibrinogen deficiency
presence of thrombolytic agent
presence of FDP and FSP
presence of heparin

Question 19

normal value for thrombin time

Answer 19

10-14 seconds

Question 20

specimen for thrombin time?

Answer 20

PPP + thrombin

Question 21

detects fibrinogen deficiency uses reptilase

Answer 21

reptilase time

Question 22

Reptilase time is prolonged in? (FPP)

Answer 22

Fibrinogen deficiency
Presence of thrombolytic agent
Presence of FDP and FSP

Question 23

normal value for reptilase time

Answer 23

10-15 seconds

Question 24

detects factor 13/XIII deficiency

Answer 24

Duckert’s test/5M urea solubility test

Question 25

Reagents of Duckerts Test

Answer 25

5M urea
1% monochloroacetic acid
2% acetic acid

Question 26

positive for Factor 13 deficiency in duckert’s test shows?

Answer 26

solubility to 5M urea at RT

Question 27

used to identify individual factor deficiency by mixing correction reagents with patient’s plasma and then performing PT and aPTT

Answer 27

Substitution studies/Mixing Studies