Test 4 Study Guide Flashcards

1
Q

Surfactant replacement therapy is for
_____

A

Respiratory distress

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2
Q

____ is the most common cause of death of surfactant deficiency

A

Pediatric RDS

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3
Q

Surfactant reduces _____

A

Surface tension

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4
Q

Alveoli is formed at ____ weeks

A

32 weeks

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5
Q

_____ prevents alveolar collapse during exhalation

A

Surface tension

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6
Q

The stage when type II cells mature

A

22 weeks

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7
Q

Any baby over ____ weeks can be saved.

A

22 weeks

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8
Q

Steroid given 24-48 hours before delivery to speed up lung development

A

Dexamethasone

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9
Q

_____ is prevention treatment

A

Prophylactic

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10
Q

Two main strategies for the prevention of neonatal ARDS in cases of preterm delivery

A
  1. Antenatal administration of hormones
  2. Prophylactic treatment with surfactant soon after birth
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11
Q

Surfactant accelerates ______ pneumocytes

A

Type II pneumocytes

( increase exchange and improve lung mechanics. Maximal lung volume, compliance and gas exchange.)

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12
Q

Administration of surfactant is based on ____ and ____

A

gestational age and birth weight

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13
Q

Outcomes of surfactant

A

Increased compliance
Decreased WOB
Decreased shunting
Decreased atelectasis
Improvement of shunt ratio

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14
Q

Can’t survive without ___ protein

A

B protein

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15
Q

Rescue surfactant is only for ____

A

ARDS

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16
Q

Surfactant is given in the ____ position

A

Supine

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17
Q

Complications of surfactant

A

Plugging of the ETT
Bradycardia

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18
Q

The temperature for surfactant should be ____

A

Room temperature

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19
Q

You need _____ for surfactant delivery

A

Multiaccess

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20
Q

_____ stage continues after birth

A

Alveolar postnatal stage

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21
Q

Layer where lung tissue is formed

A

Endodermic layer

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22
Q

Stage that occurs during gestational weeks of 7-17

A

Pseudoglandular stage

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23
Q

Stage in which the alveolar sac develops

A

Canalicular stage

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24
Q

Stage develops between 17-26 weeks

A

Canalicular stage

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25
Formulation of type I and type II pneumocytes
20-22 weeks gestation (Canalicular stage)
26
Stage between 27-36 weeks
Saccular stage
27
Alveoli appear at _____ weeks gestation
32 weeks
28
All conducting airways and respiratory branches are in place by ____ weeks
36 weeks
29
____ stage is 36 weeks gestation through after birth
Alveolar stage
30
_____ retains surfactant and aids in its distribution
Tubular myelin
31
Can cause difficulty breathing and decreased gas exchange
Overexpansion of the lungs
32
____ blocks inflammatory mediator production
Protein A and D
33
decreased number of airways, cells, alveoli. Can be caused by tumor or anything that takes up more space in the lungs. Very rare. Decreased size and weight of lungs.
Pulmonary hypoplasia
34
the most common condition associated with restricted growth due to lung compression.
Congenital diaphragmatic hernia (CDH)
35
_______ is important as it provides a barrier against infection
Amniotic fluid
36
abnormally high level of fluid
Polyhydramnios
37
inadequate level of fluid
Oligohydramnios
38
Most common cause of respiratory distress in neonates
Pediatric ARDS
39
Signs of pediatric ARDS
Retractions, grunting = NOT CYANOSIS
40
At 28 weeks, ____ hasn't developed yet and should be given through the ETT
Surfactant
41
Normal pediatric RR
30-60
42
Normal pediatric SPO2
>88%
43
Normal pediatric blood pressure
80/50
44
Normal pediatric HR
120-160
45
Baby Tory - 28 week c section, 140 HR, 49 RR, 35, 82% What should we do?
Surfactant STAT through ETT then bubble CPAP for oxygenation
46
____ can check if baby has surfactant production before birth
Amniocentesis
47
Natural surfactant can come from ____
Cows and pigs
48
____ surfactant is made in a lab from protein B and C
Synthetic surfactant
49
When do we need HFNC v. CPAP?
HFNC is just for oxygenation. CPAP is for ventilation and oxygenation (baby BIPAP).
50
3 layers
Endoderm Mesoderm Ectoderm
51
Endoderm produces ___
the cecum, intestine, stomach, liver, digestive tract
52
Ectoderm produces ____
Sensory and skin
53
Mesoderm produces _____
heart and lung, connective tissues
54
Valve formation creates ______ blood flow.
unidirectional
55
____ creates circulation between mother and child and that’s where gas exchange occurs
Placenta
56
____ removes waste from the fetus’ blood and acts as a barrier to protection the fetus from infection
Placenta
57
____ provides oxygenated blood to the fetus
Umbilical vein
58
_____ removes deoxygenated blood from the fetus
Umbilical artery
59
______ connects umbilical vein and inferior vena cava.
Ductus venosus
60
oxygenated blood from placenta enters the fetus through the _____
Umbilical vein
61
Blood bypasses the liver via _____
ductus venosus
62
Blood bypasses the liver through the ductus venosus and enters the ______
inferior vena cava
63
1. Oxygenated blood from placenta enters the fetus through umbilical vein. 2. Blood bypasses liver via the ductus venosus 3. From ductus venosus, enters inferior vena cava. 4. From inferior vena cava, blood enters R atrium 5. From R atrium goes to L atrium through Field and bypasses lungs.