Test 4 Study Guide Flashcards

1
Q

Surfactant replacement therapy is for
_____

A

Respiratory distress

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2
Q

____ is the most common cause of death of surfactant deficiency

A

Pediatric RDS

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3
Q

Surfactant reduces _____

A

Surface tension

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4
Q

Alveoli is formed at ____ weeks

A

32 weeks

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5
Q

_____ prevents alveolar collapse during exhalation

A

Surface tension

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6
Q

The stage when type II cells mature

A

22 weeks

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7
Q

Any baby over ____ weeks can be saved.

A

22 weeks

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8
Q

Steroid given 24-48 hours before delivery to speed up lung development

A

Dexamethasone

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9
Q

_____ is prevention treatment

A

Prophylactic

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10
Q

Two main strategies for the prevention of neonatal ARDS in cases of preterm delivery

A
  1. Antenatal administration of hormones
  2. Prophylactic treatment with surfactant soon after birth
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11
Q

Surfactant accelerates ______ pneumocytes

A

Type II pneumocytes

( increase exchange and improve lung mechanics. Maximal lung volume, compliance and gas exchange.)

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12
Q

Administration of surfactant is based on ____ and ____

A

gestational age and birth weight

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13
Q

Outcomes of surfactant

A

Increased compliance
Decreased WOB
Decreased shunting
Decreased atelectasis
Improvement of shunt ratio

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14
Q

Can’t survive without ___ protein

A

B protein

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15
Q

Rescue surfactant is only for ____

A

ARDS

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16
Q

Surfactant is given in the ____ position

A

Supine

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17
Q

Complications of surfactant

A

Plugging of the ETT
Bradycardia

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18
Q

The temperature for surfactant should be ____

A

Room temperature

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19
Q

You need _____ for surfactant delivery

A

Multiaccess

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20
Q

_____ stage continues after birth

A

Alveolar postnatal stage

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21
Q

Layer where lung tissue is formed

A

Endodermic layer

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22
Q

Stage that occurs during gestational weeks of 7-17

A

Pseudoglandular stage

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23
Q

Stage in which the alveolar sac develops

A

Canalicular stage

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24
Q

Stage develops between 17-26 weeks

A

Canalicular stage

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25
Q

Formulation of type I and type II pneumocytes

A

20-22 weeks gestation (Canalicular stage)

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26
Q

Stage between 27-36 weeks

A

Saccular stage

27
Q

Alveoli appear at _____ weeks gestation

A

32 weeks

28
Q

All conducting airways and respiratory branches are in place by ____ weeks

A

36 weeks

29
Q

____ stage is 36 weeks gestation through after birth

A

Alveolar stage

30
Q

_____ retains surfactant and aids in its distribution

A

Tubular myelin

31
Q

Can cause difficulty breathing and decreased gas exchange

A

Overexpansion of the lungs

32
Q

____ blocks inflammatory mediator production

A

Protein A and D

33
Q

decreased number of airways, cells, alveoli. Can be caused by tumor or anything that takes up more space in the lungs. Very rare. Decreased size and weight of lungs.

A

Pulmonary hypoplasia

34
Q

the most common condition associated with restricted growth due to lung compression.

A

Congenital diaphragmatic hernia (CDH)

35
Q

_______ is important as it provides a barrier against infection

A

Amniotic fluid

36
Q

abnormally high level of fluid

A

Polyhydramnios

37
Q

inadequate level of fluid

A

Oligohydramnios

38
Q

Most common cause of respiratory distress in neonates

A

Pediatric ARDS

39
Q

Signs of pediatric ARDS

A

Retractions, grunting = NOT CYANOSIS

40
Q

At 28 weeks, ____ hasn’t developed yet and should be given through the ETT

A

Surfactant

41
Q

Normal pediatric RR

A

30-60

42
Q

Normal pediatric SPO2

A

> 88%

43
Q

Normal pediatric blood pressure

A

80/50

44
Q

Normal pediatric HR

A

120-160

45
Q

Baby Tory - 28 week c section, 140 HR, 49 RR, 35, 82%

What should we do?

A

Surfactant STAT through ETT then bubble CPAP for oxygenation

46
Q

____ can check if baby has surfactant production before birth

A

Amniocentesis

47
Q

Natural surfactant can come from ____

A

Cows and pigs

48
Q

____ surfactant is made in a lab from protein B and C

A

Synthetic surfactant

49
Q

When do we need HFNC v. CPAP?

A

HFNC is just for oxygenation. CPAP is for ventilation and oxygenation (baby BIPAP).

50
Q

3 layers

A

Endoderm
Mesoderm
Ectoderm

51
Q

Endoderm produces ___

A

the cecum, intestine, stomach, liver, digestive tract

52
Q

Ectoderm produces ____

A

Sensory and skin

53
Q

Mesoderm produces _____

A

heart and lung, connective tissues

54
Q

Valve formation creates ______ blood flow.

A

unidirectional

55
Q

____ creates circulation between mother and child and that’s where gas exchange occurs

A

Placenta

56
Q

____ removes waste from the fetus’ blood and acts as a barrier to protection the fetus from infection

A

Placenta

57
Q

____ provides oxygenated blood to the fetus

A

Umbilical vein

58
Q

_____ removes deoxygenated blood from the fetus

A

Umbilical artery

59
Q

______ connects umbilical vein and inferior vena cava.

A

Ductus venosus

60
Q

oxygenated blood from placenta enters the fetus through the _____

A

Umbilical vein

61
Q

Blood bypasses the liver via _____

A

ductus venosus

62
Q

Blood bypasses the liver through the ductus venosus and enters the ______

A

inferior vena cava

63
Q
  1. Oxygenated blood from placenta enters the fetus through umbilical vein.
  2. Blood bypasses liver via the ductus venosus
  3. From ductus venosus, enters inferior vena cava.
  4. From inferior vena cava, blood enters R atrium
  5. From R atrium goes to L atrium through Field and bypasses lungs.
A