Test 4: Normal Oral Microbiota Flashcards

1
Q

What makes the oral cavity a hospitable place for microbes?

A

-warm, moist, constant source of nutrition

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2
Q

What are the 3 ecological niches provided by the human host?

A
  • dorsum of tongue
  • clinical crowns of teeth
  • gingival sulcus
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3
Q

Which niche has the lowest concentration of organisms and what is its concentration?

A

Dorsum of tongue

-7.5*10^8/mL saliva

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4
Q

Which niche is the most aerobic?

A

Dorsum of tongue

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5
Q

Which niche provides the most different types of substrates for bacterial attachment?

A

Gingival sulcus: hard and soft tissue

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6
Q

What niche is the most anaerobic?

A

Gingival sulcus

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7
Q

What type of inter-species interaction increases the diversity of organisms?

A

Neutral and Cooperative/beneficial

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8
Q

Which inter-species interaction limits colonization of systemic pathogens?

A

Antagonistic/inhibitory

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9
Q

Which method of identification gives the largest number of organisms?

A

Total Count: includes both live and dead organisms

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10
Q

Which method of identification is the best for identifying different organisms?

A

Analysis of 16s ribosomal subunits (DNA sequencing)

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11
Q

In what groups of people are stable organisms found?

A

Adults with at least some anterior and posterior teeth (not young people or old edentulous people)

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12
Q

What is one of the first organisms to colonize after birth?

A

Streptococcus salivarius

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13
Q

What medium is used to grow oral streptococci?

A

Mitus-salivarius

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14
Q

What type of hemolysis mechanism to most streptococci use?

A

Alpha-hemolysis

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15
Q

Which microbes are considered systemic pathogens? **

A
  • Strep sanguis
  • Staph aureus
  • Peptostreptococcus anaerobius
  • Neisseria gonorrhoeae
  • Acintomyces israelli
  • Candida Albicans
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16
Q

Where is strep salivarius predominantly found?

A
  • makes up 50% of count from dorsum of tongue

- soft tissue

17
Q

Where is strep sanguis predominantly found?

A

Supragingival plaque

18
Q

What systemic disease is srep sanguis associated with?

A

Infective Endocarditis

19
Q

Which oral streptococci is cariogenic?

A

Strep mutans; aciduric and acidogenic

20
Q

What does staph aureus commonly cause?

A

Osteomyelitis

21
Q

Where in the oral cavity can peptostreptococcus anaerobius be found?

A
  • gingival sulcus, infected pulp, dental abscesses

- obligate anaerobe

22
Q

What systemic disease is assocaited with peptostreptococcus anaerobius?

A

Ludwigs angina (enlargement and swelling of neck from cellular infiltrate)

23
Q

What are the most populous groups in the oral cavity?

A

Oral Strep and Veillonella parvula

24
Q

What type of relationship does veillonella parvula have with strep mutans?

A

Beneficial: VP can’t ferment carbs because they lack the kinases, require intermediate metabolites created by strep mutans

25
What is the most common oral microbe?
Neisseria Sicca
26
How does lactobaccilli compare to strep mutans (aciduric/acidogenic)?
-More aciduric but less acidogenic
27
When does the population of lactobacillus acidophilus increase?
In a carious lesion--continues the process into dentin
28
What is the difference between homofermenters of lactobacilli and heterofermenters?
Homo: produce > 65% lactic acid as end product Hetero: makes <65% lactic acid; also acetic acid, ethanol, and CO2
29
What bacteria can induce root caries?
Actinomyces (naeslundii and viscosus): facultative anaerobes
30
What bacteria can cause actinomycosis (surgical space infections)?
Actinomyces israelli
31
What species are considered bacteroides (gram neg anaerobic rods)?
Prophyromonas gingivalis, prevotella intermedia, bacteroides forsythus, and bacteroides gracilis
32
Where are bacteroides primarily found?
Periopathogens found in gingival sulcus
33
Which organism is predominantly found in gingival crevice with juvenile/aggressive perio?
agregatibacter actinomycetemcomitans
34
Which group is highly motile found in gingival sulcus?
spirochetes
35
What bacteria are associated with ANUG?
Treponema vincentii and fusobacterium nucleatum
36
What is the most common pathogenic oral fungus?
Candida albicans