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DMIC 5001 > Test 4: Normal Oral Microbiota > Flashcards

Test 4: Normal Oral Microbiota Flashcards

1
Q

What makes the oral cavity a hospitable place for microbes?

A

-warm, moist, constant source of nutrition

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2
Q

What are the 3 ecological niches provided by the human host?

A
  • dorsum of tongue
  • clinical crowns of teeth
  • gingival sulcus
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3
Q

Which niche has the lowest concentration of organisms and what is its concentration?

A

Dorsum of tongue

-7.5*10^8/mL saliva

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4
Q

Which niche is the most aerobic?

A

Dorsum of tongue

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5
Q

Which niche provides the most different types of substrates for bacterial attachment?

A

Gingival sulcus: hard and soft tissue

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6
Q

What niche is the most anaerobic?

A

Gingival sulcus

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7
Q

What type of inter-species interaction increases the diversity of organisms?

A

Neutral and Cooperative/beneficial

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8
Q

Which inter-species interaction limits colonization of systemic pathogens?

A

Antagonistic/inhibitory

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9
Q

Which method of identification gives the largest number of organisms?

A

Total Count: includes both live and dead organisms

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10
Q

Which method of identification is the best for identifying different organisms?

A

Analysis of 16s ribosomal subunits (DNA sequencing)

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11
Q

In what groups of people are stable organisms found?

A

Adults with at least some anterior and posterior teeth (not young people or old edentulous people)

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12
Q

What is one of the first organisms to colonize after birth?

A

Streptococcus salivarius

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13
Q

What medium is used to grow oral streptococci?

A

Mitus-salivarius

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14
Q

What type of hemolysis mechanism to most streptococci use?

A

Alpha-hemolysis

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15
Q

Which microbes are considered systemic pathogens? **

A
  • Strep sanguis
  • Staph aureus
  • Peptostreptococcus anaerobius
  • Neisseria gonorrhoeae
  • Acintomyces israelli
  • Candida Albicans
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16
Q

Where is strep salivarius predominantly found?

A
  • makes up 50% of count from dorsum of tongue

- soft tissue

17
Q

Where is strep sanguis predominantly found?

A

Supragingival plaque

18
Q

What systemic disease is srep sanguis associated with?

A

Infective Endocarditis

19
Q

Which oral streptococci is cariogenic?

A

Strep mutans; aciduric and acidogenic

20
Q

What does staph aureus commonly cause?

A

Osteomyelitis

21
Q

Where in the oral cavity can peptostreptococcus anaerobius be found?

A
  • gingival sulcus, infected pulp, dental abscesses

- obligate anaerobe

22
Q

What systemic disease is assocaited with peptostreptococcus anaerobius?

A

Ludwigs angina (enlargement and swelling of neck from cellular infiltrate)

23
Q

What are the most populous groups in the oral cavity?

A

Oral Strep and Veillonella parvula

24
Q

What type of relationship does veillonella parvula have with strep mutans?

A

Beneficial: VP can’t ferment carbs because they lack the kinases, require intermediate metabolites created by strep mutans

25
Q

What is the most common oral microbe?

A

Neisseria Sicca

26
Q

How does lactobaccilli compare to strep mutans (aciduric/acidogenic)?

A

-More aciduric but less acidogenic

27
Q

When does the population of lactobacillus acidophilus increase?

A

In a carious lesion–continues the process into dentin

28
Q

What is the difference between homofermenters of lactobacilli and heterofermenters?

A

Homo: produce > 65% lactic acid as end product
Hetero: makes <65% lactic acid; also acetic acid, ethanol, and CO2

29
Q

What bacteria can induce root caries?

A

Actinomyces (naeslundii and viscosus): facultative anaerobes

30
Q

What bacteria can cause actinomycosis (surgical space infections)?

A

Actinomyces israelli

31
Q

What species are considered bacteroides (gram neg anaerobic rods)?

A

Prophyromonas gingivalis, prevotella intermedia, bacteroides forsythus, and bacteroides gracilis

32
Q

Where are bacteroides primarily found?

A

Periopathogens found in gingival sulcus

33
Q

Which organism is predominantly found in gingival crevice with juvenile/aggressive perio?

A

agregatibacter actinomycetemcomitans

34
Q

Which group is highly motile found in gingival sulcus?

A

spirochetes

35
Q

What bacteria are associated with ANUG?

A

Treponema vincentii and fusobacterium nucleatum

36
Q

What is the most common pathogenic oral fungus?

A

Candida albicans

DMIC 5001 (15 decks)

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