Test 4 Medications Flashcards
Which medications are used to treat Guillian-Barre?
Plasampherisis
Anticoagulants
Gabapentin
TCAs
What medication is used to treat Myasthenia Gravis?
Anticholinesteraseses
Immunosuppressants
Corticosteroids
IVIG
Which medications are used to treat Parkinson’s?
Dopamine Agonists (Pramipexole)
Dopaminergics (Levodopa/carbidopa)
Anticholinergics (Benztropine)
COMT Inhibitors (Entacapone)
What is the action of a Pramipexole?
A dopamine agonist used to treat Parkinson’s that causes an active release of dopamine
What is the action of Levodopa/carbidopa?
Levodopa is a medication used to treat Parkinson’s that is an inactive form of dopamine that is then activated in the brain after carbidopa transports it across the BBB.
What are the side effects of pramipexole?
N/V
Postural hypertension
Dyskinesias
Dizziness
Light-headness
Confusion
Hallucinations
What diet should be followed when taking levidopa/carbidopa?
It should be taken with food, but not with high protein due to competitive absorption
What is a COMT inhibitor (Entacapone)?
Decreases levodopa breakdown
What are the side effects of entacapone?
Dyskinesias
Hyperkinesias
Diarrhea
Dark Urine
What is Phenytoin (Dilantin)?
A medication used to prevent and treat tonic-clonic seizures, partial seizures, status epilepticus that is given PO or IV
What is the therapeutic range of Phenytoin/Dilantin?
10-20
What are the side effects o Phenytoin/Dilantin?
Hypotension
Arrythmias
Gum hyperplasia
Nystagmus
Hirsutism
Blocks absorption of folic acid
Blocks oral contraceptive
Extraversion of IV can cause purple glove
Harry Apes Have Great Necks But Barly Eat
What is Fosphenytoin (Cerebyx)?
A medication developed for decreased adverse effects of parenteral phenytoin either IV or IM that can be fgiven more rapidly and less likely to cause hypotension
What seizure drug must NEVER be given IM due to caustic injury to muscles?
Phenytoin (Dilantin)
What are the disadvantages to Fosphenytoin?
It can take 8-10 minutes to metabolize & reach peak concentration (can’t abort status epilepticus)
SE similar to phenytoin but less pronounced
Can develop prutritus
Requires transition to PO for home mainentance
What drugs are used to treat status epilepticus?
IVP Benzos (lorazapam/diazepam)
IV phenytoin
Diazapam Rectal gel (if not IV access)
What medications are used to treat HTN in diabetics?
ACE-1 or ARB to start
Thiazide Diuretic
What medications are used to treat hyperlipidema in diabetics?
Statin Therapy
ASA (antiplatlets)for CVD