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General Biology One > Test 3 > Flashcards

Test 3 Flashcards

1
Q

In multicellular organisms, one of many types of secreted chemicals that are formed in specialized cells, travel in body fluids, and act on specific target cells in other parts of the organism, changing the target cells’ functioning.

A

Hormone

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2
Q

A series of steps linking a mechanical, chemical, or electrical stimulus to a specific cellular response.

A

Signal transduction pathway

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3
Q

A molecule that binds specifically to another molecule, usually a larger one.

A

Ligand

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4
Q

An enzyme that transfers phosphate groups from ATP to a protein, thus phosphorylating the protein.

A

Protein kinase

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5
Q

A series of chemical reactions during cell signaling mediated by enzymes (kinases), in which each kinase in turn phosphorylates and activates another, ultimately leading to phosphorylation of many proteins.

A

Phosphorylation cascade

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6
Q

An enzyme that removes phosphate groups from (dephosphorylates) proteins, often functioning to reverse the effect of a protein kinase.

A

Protein phosphatase

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7
Q

Cyclic adenosine monophosphate, a ring-shaped molecule made from ATP that is a common intracellular signaling molecule (second messenger) in eukaryotic cells.

A

Cyclic amp (cAMP)

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8
Q

An enzyme that converts ATP to cyclic AMP in response to an extracellular signal.

A

Adenylyl Cyclase

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9
Q

A second messenger that functions as an intermediate between certain signaling molecules and a subsequent second messenger, Ca2+, by causing a rise in cytoplasmic Ca2+ concentration.

A

Inositol triphosphate

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10
Q

A second messenger produced by the cleavage of the phospholipid PIP 2 in the plasma membrane.

A

Diacylglycerol

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11
Q

A type of large relay protein to which several other relay proteins are simultaneously attached, increasing the efficiency of signal transduction.

A

Scaffolding protein

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12
Q

A type of programmed cell death, which is brought about by activation of enzymes that break down many chemical components in the cell.

A

Apoptosis

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13
Q

The genetic material of an organism or virus; the complete complement of an organism’s or virus’s genes along with its noncoding nucleic acid sequences.

A

Genome

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14
Q

A cellular structure consisting of one DNA molecule and associated protein molecules.

A

Chromosome

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15
Q

The complex of DNA and proteins that makes up eukaryotic chromosomes.

A

Chromatin

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16
Q

Any cell in a multicellular organism except a sperm or egg or their precursors.

A

Somatic cell

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17
Q

A haploid reproductive cell, such as an egg or sperm, that is formed by meiosis or is the descendant of cells formed by meiosis.

A

Gamete

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18
Q

Two copies of a duplicated chromosome attached to each other by proteins at the centromere and, sometimes, along the arms.

A

Sister chromatids

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19
Q

In a duplicated chromosome, the region on each sister chromatid where it is most closely attached to its sister chromatid by proteins that bind to the centromeric DNA.

A

Centromere

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20
Q

A process of nuclear division in eukaryotic cells conventionally divided into five stages: prophase, prometaphase, metaphase, anaphase, and telophase

A

Mitosis

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21
Q

The division of the cytoplasm to form two separate daughter cells immediately after mitosis, meiosis I, or meiosis II.

A

Cytokinesis

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22
Q

The phase of the cell cycle that includes mitosis and cytokinesis.

A

Mitotic phase (M phase)

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23
Q

The period in the cell cycle when the cell is not dividing.

A

Interphase

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24
Q

The first gap, or growth phase, of the cell cycle, consisting of the portion of interphase before DNA synthesis begins.

A

G1 phase

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25
Q

The synthesis phase of the cell cycle; the portion of interphase during which DNA is replicated.

A

S phase

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26
Q

The second gap, or growth phase, of the cell cycle, consisting of the portion of interphase after DNA synthesis occurs.

A

G2 phase

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27
Q

The first stage of mitosis, in which the chromatin condenses into discrete chromosomes visible with a light microscope, the mitotic spindle begins to form, and the nucleolus disappears but the nucleus remains intact.

A

Prophase

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28
Q

The second stage of mitosis, in which the nuclear envelope fragments and the spindle microtubules attach to the kinetochores of the chromosomes.

A

Prometaphase

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29
Q

The third stage of mitosis, in which the spindle is complete and the chromosomes, attached to microtubules at their kinetochores, are all aligned at the metaphase plate.

A

Metaphase

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30
Q

The fourth stage of mitosis, in which the chromatids of each chromosome have separated and the daughter chromosomes are moving to the poles of the cell.

A

Anaphase

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31
Q

The fifth and final stage of mitosis, in which daughter nuclei are forming and cytokinesis has typically begun.

A

Telophase

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32
Q

An assemblage of microtubules and associated proteins that is involved in the movement of chromosomes during mitosis.

A

Mitotic spindle

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33
Q

A structure present in the cytoplasm of animal cells that functions as a microtubule-organizing center and is important during cell division.

A

Centrosome

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34
Q

A structure of proteins attached to the centromere that links each sister chromatid to the mitotic spindle.

A

Kinetochore

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35
Q

An imaginary structure located at a plane midway between the two poles of a cell in metaphase on which the centromeres of all the duplicated chromosomes are located.

A

Metaphase plate

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36
Q

The process of cytokinesis in animal cells, characterized by pinching of the plasma membrane.

A

Cleavage

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37
Q

The first sign of cleavage in an animal cell; a shallow groove around the cell in the cell surface near the old metaphase plate.

A

Cleavage furrow

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38
Q

A membrane-bounded, flattened sac located at the midline of a dividing plant cell, inside which the new cell wall forms during cytokinesis.

A

Cell plate

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39
Q

A method of asexual reproduction in single-celled organisms in which the cell grows to roughly double its size and then divides into two cells.

A

Binary fission

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40
Q

Site where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides.

A

Origin of replication

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41
Q

A cyclically operating set of molecules in the eukaryotic cell that both triggers and coordinates key events in the cell cycle.

A

Cell cycle control system

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42
Q

A control point in the cell cycle where stop and go-ahead signals can regulate the cycle.

A

Checkpoint

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43
Q

A cellular protein that occurs in a cyclically fluctuating concentration and that plays an important role in regulating the cell cycle.

A

Cyclin

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44
Q

A protein kinase that is active only when attached to a particular cyclin.

A

Cyclin-dependent kinases

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45
Q

Maturation-promoting factor

A

MPF

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46
Q

A nondividing state occupied by cells that have left the cell cycle, sometimes reversibly.

A

G0 phase

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47
Q

A protein that must be present in the extracellular environment (culture medium or animal body) for the growth and normal development of certain types of cells.

A

Growth factor

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48
Q

The phenomenon observed in normal animal cells that causes them to stop dividing when they come into contact with one another.

A

Density dependent inhibition

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49
Q

The requirement that a cell must be attached to a substratum in order to initiate cell division.

A

Anchorage dependence

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50
Q

The process by which a cell in culture acquires the ability to divide indefinitely, similar to the division of cancer cells.

A

Transformation

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51
Q

A mass of abnormal cells with specific genetic and cellular changes such that the cells are not capable of surviving at a new site and generally remain at the site of the tumor’s origin.

A

Benign tumor

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52
Q

A cancerous tumor containing cells that have significant genetic and cellular changes and are capable of invading and surviving in new sites.

A

Malignant tumor

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53
Q

The spread of cancer cells to locations distant from their original site.

A

Metastasis

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54
Q

The transmission of traits from one generation to the next.

A

Heredity

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55
Q

Differences between members of the same species.

A

Variation

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56
Q

The scientific study of heredity and hereditary variation.

A

Genetics

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57
Q

A discrete unit of hereditary information consisting of a specific nucleotide sequence in DNA

A

Gene

58
Q

A haploid reproductive cell, such as an egg or sperm, that is formed by meiosis or is the descendant of cells formed by meiosis.

A

Gamete

59
Q

A specific place along the length of a chromosome where a given gene is located.

A

Locus

60
Q

The generation of offspring from a single parent that occurs without the fusion of gametes.

A

Asexual reproduction

61
Q

A lineage of genetically identical individuals or cells.

A

Clone

62
Q

Reproduction arising from fusion of two gametes.

A

Sexual reproduction

63
Q

The generation-to-generation sequence of stages in the reproductive history of an organism.

A

Life cycle

64
Q

A display of the chromosome pairs of a cell arranged by size and shape.

A

Karyotype

65
Q

A pair of chromosomes of the same length, centromere position, and staining pattern that possess genes for the same characters at corresponding loci.

A

Homologous chromosomes

66
Q

A chromosome responsible for determining the sex of an individual.

A

Sex chromosomes

67
Q

A chromosome that is not directly involved in determining sex; not a sex chromosome.

A

Autosomes

68
Q

A cell containing two sets of chromosomes (2n), one set inherited from each parent.

A

Diploid cell

69
Q

A cell containing only one set of chromosomes

A

Haploid cell

70
Q

The union of haploid gametes to produce a diploid zygote.

A

Fertilization

71
Q

The diploid cell produced by the union of haploid gametes during fertilization;

A

Zygote

72
Q

A life cycle in which there is both a multicellular diploid form, the sporophyte, and a multicellular haploid form, the gametophyte

A

Alteration of generations

73
Q

The first division of a two-stage process of cell division in sexually reproducing organisms that results in cells with half the number of chromosome sets as the original cell.

A

Meiosis 1

74
Q

The second division of a two-stage process of cell division in sexually reproducing organisms that results in cells with half the number of chromosome sets as the original cell.

A

Meiosis 2

75
Q

complex A zipper-like structure composed of proteins, which connects a chromosome to its homolog tightly along their lengths during part of prophase I of meiosis.

A

Synaptonemal complex

76
Q

The pairing and physical connection of one duplicated chromosome to its homolog during prophase I of meiosis.

A

Synopsis

77
Q

A chromosome created when crossing over combines DNA from two parents into a single chromosome.

A

Recombinant chromosome

78
Q

An observable heritable feature that may vary among individuals.

A

Character

79
Q

One of two or more detectable variants in a genetic character.

A

Trait

80
Q

Referring to organisms that produce offspring of the same variety over many generations of self-pollination.

A

True breeding

81
Q

In genetics, the mating, or crossing, of two true-breeding varieties.

A

Hybridization

82
Q

The true-breeding (homozygous) parent individuals from which F 1 hybrid offspring are derived in studies of inheritance

A

P generation

83
Q

The first filial, hybrid (heterozygous) offspring arising from a parental (P generation) cross.

A

F1 generation

84
Q

The offspring resulting from interbreeding (or self-pollination) of the hybrid F 1 generation.

A

F2 generation

85
Q

Any of the alternative versions of a gene that may produce distinguishable phenotypic effects.

A

Allele

86
Q

An allele that is fully expressed in the phenotype of a heterozygote.

A

Dominant allele

87
Q

An allele whose phenotypic effect is not observed in a heterozygote.

A

Recessive allele

88
Q

Mendel’s first law, stating that the two alleles in a pair segregate (separate from each other) into different gametes during gamete formation.

A

Law of segregation

89
Q

A diagram used in the study of inheritance to show the predicted genotypic results of random fertilization in genetic crosses between individuals of known genotype.

A

Punnet square

90
Q

An organism that has a pair of identical alleles for a gene (encoding a character).

A

Homozygote

91
Q

Having two identical alleles for a given gene.

A

Homozygous

92
Q

An organism that has two different alleles for a gene (encoding a character).

A

Heterozygote

93
Q

Having two different alleles for a given gene.

A

Heterozygous

94
Q

The observable physical and physiological traits of an organism, which are determined by its genetic makeup.

A

Phenotype

95
Q

The genetic makeup, or set of alleles, of an organism.

A

Genotype

96
Q

Breeding an organism of unknown genotype with a homozygous recessive individual to determine the unknown genotype.

A

Testcross

97
Q

An organism that is heterozygous with respect to a single gene of interest.

A

Monohybrid

98
Q

A cross between two organisms that are heterozygous for the character being followed

A

Monohybrid cross

99
Q

An organism that is heterozygous with respect to two genes of interest

A

Dihybrid

100
Q

A cross between two organisms that are each heterozygous for both of the characters being followed

A

Dihybrid cross

101
Q

Mendel’s second law, stating that each pair of alleles segregates, or assorts, independently of each other pair during gamete formation

A

Law of independent assortment

102
Q

A rule of probability stating that the probability of two or more independent events occurring together can be determined by multiplying their individual probabilities.

A

Multiplication rule

103
Q

A rule of probability stating that the probability of any one of two or more mutually exclusive events occurring can be determined by adding their individual probabilities.

A

Addition rule

104
Q

The situation in which the phenotypes of the heterozygote and dominant homozygote are indistinguishable.

A

Complete dominance

105
Q

The situation in which the phenotype of heterozygotes is intermediate between the phenotypes of individuals homozygous for either allele.

A

Incomplete dominance

106
Q

The situation in which the phenotypes of both alleles are exhibited in the heterozygote because both alleles affect the phenotype in separate, distinguishable ways.

A

Codominance

107
Q

A human genetic disease caused by a recessive allele for a dysfunctional enzyme, leading to accumulation of certain lipids in the brain.

A

Tay-Sachs disease

108
Q

The ability of a single gene to have multiple effects.

A

Pleiotropy

109
Q

A type of gene interaction in which the phenotypic expression of one gene alters that of another independently inherited gene.

A

Epistasis

110
Q

A heritable feature that varies continuously over a range rather than in an either-or fashion.

A

Quantitative character

111
Q

An additive effect of two or more genes on a single phenotypic character.

A

Polygenic inheritance

112
Q

Referring to a phenotypic character that is influenced by multiple genes and environmental factors.

A

Multifactorial

113
Q

A diagram of a family tree with conventional symbols, showing the occurrence of heritable characters in parents and offspring over multiple generations.

A

Pedigree

114
Q

In genetics, an individual who is heterozygous at a given genetic locus for a recessively inherited disorder.

A

Carriers

115
Q

A human genetic disorder caused by a recessive allele for a chloride channel protein

A

Cystic fibrosis

116
Q

A recessively inherited human blood disorder in which a single nucleotide change in the a-globin gene causes hemoglobin to aggregate, changing red blood cell shape and causing multiple symptoms in afflicted individuals.

A

Sickle-cell disease

117
Q

A human genetic disease caused by a dominant allele

A

Huntington’s disease

118
Q

A basic principle in biology stating that genes are located at specific positions (loci) on chromosomes and that the behavior of chromosomes during meiosis accounts for inheritance patterns.

A

Chromosome theory of inheritance

119
Q

The phenotype most commonly observed in natural populations

A

Wild type

120
Q

A gene located on either sex chromosome. Most sex-linked genes are on the X chromosome and show distinctive patterns of inheritance

A

Sex-linked gene

121
Q

A gene located on the X chromosome

A

X-linked gene

122
Q

A human genetic disease caused by a sex-linked recessive allele

A

Dechenne muscular distrophy

123
Q

A human genetic disease caused by a sex-linked recessive allele resulting in the absence of one or more blood-clotting proteins

A

Hemophilia

124
Q

A dense object lying along the inside of the nuclear envelope in cells of female mammals, representing a highly condensed, inactivated X chromosome.

A

Barr body

125
Q

Genes located close enough together on a chromosome that they tend to be inherited together.

A

Linked genes

126
Q

General term for the production of offspring with combinations of traits that differ from those found in either parent.

A

Genetic recombination

127
Q

An offspring with a phenotype that matches one of the true-breeding parental (P generation) phenotypes

A

Parental type

128
Q

An offspring whose phenotype differs from that of the true-breeding P generation parents

A

Recombinant types/recombinant

129
Q

The reciprocal exchange of genetic material between nonsister chromatids during prophase I of meiosis.

A

Crossing over

130
Q

An ordered list of genetic loci (genes or other genetic markers) along a chromosome.

A

Genetic map

131
Q

An error in meiosis or mitosis in which members of a pair of homologous chromosomes or a pair of sister chromatids fail to separate properly from each other.

A

Nondisjunction

132
Q

A chromosomal aberration in which one or more chromosomes are present in extra copies or are deficient in number.

A

Aneuploidy

133
Q

Referring to a diploid cell that has only one copy of a particular chromosome instead of the normal two.

A

Monosomic

134
Q

Referring to a diploid cell that has three copies of a particular chromosome instead of the normal two.

A

Trisomic

135
Q

A chromosomal alteration in which the organism possesses more than two complete chromosome sets.

A

Polyploidy

136
Q

A deficiency in a chromosome resulting from the loss of a fragment through breakage.

A

Deletion

137
Q

An aberration in chromosome structure due to fusion with a fragment from a homologous chromosome, such that a portion of a chromosome is duplicated.

A

Duplication

138
Q

An aberration in chromosome structure resulting from reattachment of a chromosomal fragment in a reverse orientation to the chromosome from which it originated.

A

Imversion

139
Q

An aberration in chromosome structure resulting from attachment of a chromosomal fragment to a nonhomologous chromosome.

A

Translocation

140
Q

A human genetic disease usually caused by the presence of an extra chromosome 21

A

Down syndrome

141
Q

A phenomenon in which expression of an allele in offspring depends on whether the allele is inherited from the male or female parent.

A

Genomic imprinting

General Biology One (4 decks)

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