Test 3 Flashcards
Levothyroxine MOA
Synthetic thyroxine binds to the T4 receptor and imitates the reaction of T4
Levothyroxine Class
Thyroid hormone analog
Levothyroxine indications
Hypothyroidism and pituitary TSH suppression
Methimazole MOA
Inhibits oxidation of iodine in the thyroid gland, preventing T3 and T4 formation
Methimazole Class
Thiomide, Anti-Thyroid Agent
Methimazole indications
Hyperthyroidism and Graves’ disease
Propylthiouracil MOA
Inhibits oxidation of iodine in the thyroid gland, preventing T3 and T4 formation
Propylthiouracil Class
Thiomide, Anti-Thyroid Agent
Propylthiouracil indications
Hyperthyroidism and Graves’ disease
Propanolol MOA
Competitively blocks beta-adrenergic receptors
Propanolol Class
Non-specific beta-blocker
Propanolol Indicaitons
Thyrotoxicosis, thyroid storm
Iodine-131 MOA
Radiologically destroys the thryoid gland tissue through beta particle emission
Iodine-131 Class
Radiopharmaceutical antithyroid agent
Iodine-131 Indications
Hyperthyroidism, imaging modality
Bisphosphonates MOA
Binds to bone tissue and prevents osteoclast degradation
Bisphosphonates Class
Antiosteoporotic agent
Bisphosphonates Indications
Osteoporosis, Paget’s disease
Calcitonin MOA
Antagonizes effects of PTH inhibiting osteoclast bone resorption, increases renal excretion of phosphate and calcium
Calcitonin Class
Hormone
Calcitonin Indications
Osteoporosis, Paget’s disease, hypercalcemia
Calcitriol MOA
Activates vitamin D receptors to increase serum calcium and decrease PTH levels