Test 3 Flashcards
To create nucleotides is sugar (deoxyribose) connected with the phosphate group?
Yes
What are the ways that bases are always connected?
Adenine with thymine, and cytosine with guanine
What is the difference in structure between pyrimidines and purines?
Pyrimidines: single ringed, whereas purines are double ringed
Does the two of them bonding together help form the double helix structure of DNA?
Yes
What are the three parts of a nucleotide?
Sugar, phosphate group, and nitrogenous base
Does the nitrogenous base make a difference of what nucleotide you’re working with?
Yes
Is the backbone of DNA and RNA held together by covalent bonds?
Yes
Which of ATCG are pyrimidines/purines?
Pyrimidines: thymine, and cytosine. Purines: adenine, and guanine.
Do hydrogens bond with different bases?
Yes
Does the antiparallel structure refer to the two strands of DNA?
Yes
What does it mean when it is said that the two strands are antiparallel?
One strand runs in the 5’ to 3’ direction, while the other runs in the 3’ to 5’ direction
Does the 5’ end have a phosphate group attached to the 5’ carbon of the sugar?
Yes
What does the 3’ end have?
A hydroxyl group (-OH) attached to the 3’ carbon of the sugar
What did Griffith’s experiment demonstrate?
Genetic transformation in bacteria
Did he use two strains of streptococcus pneumonia to determine whether there was genetic transformation?
Yes
Was there a smooth but caused disease strain, as well as a rough and did not cause a disease?
Yes
Recall the experiment
S strain and R strain were both given to two different mines. The R-strain one survived whereas the one with the R-strain did not. The S strain was then heated and tested on another mouse, and a mix of the heat killed strain and R strain was given to the mouse given to mouse and died
Did Watson and Crick’s model provide the first accurate understanding of the double helix structure?
Yes
Was Franklin able to take the DNA and identify the double strand model?
Yes
Did the Meselson and Stahl experiment provide definitive evidence that DNA replication is semiconservative?
Yes
What does DNA replication being semiconservative mean?
Each new DNA molecule consists of one old (parental) strand and one newly synthesised one